Table 2.
Neutrophil phagocytosis, reactive oxygen species (ROS) generation and surface CD16 expression in 42 PAI patients and 27 healthy, sex- and age-matched controls. For the assessment of CD16 expression, 41 PAI patients and 27 healthy controls were studied. Values are presented as mean ± standard deviation.
PAI patients | Healthy controls | P | |
---|---|---|---|
Phagocytic index | 257 252 ± 87 162 | 299 220 ± 98 779 | 0.07 |
% Phagocytosing neutrophils | 98.0 ± 1.5 | 98.2 ± 1.2 | 0.68 |
Phagocytic activity (MFI) | 262 469 ± 88 707 | 304 941 ± 100 876 | 0.08 |
ROS generation (MFI) | 57 023 ± 26 463 | 49 915 ± 19 302 | 0.23 |
% CD16+ neutrophils | 97.46 ± 1.82 | 96.63 ± 3.04 | 0.33 |
CD16 surface density | 58 775 ± 27 559 | 68 380 ± 31 401 | 0.20 |
MFI, median fluorescence intensity. Phagocytic index calculated as (% phagocytosis/100) × phagocytic activity.