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. Author manuscript; available in PMC: 2017 May 11.
Published in final edited form as: J Neurosci Methods. 2014 Oct 12;239:65–74. doi: 10.1016/j.jneumeth.2014.10.001

Fig. 6.

Fig. 6

Injection of collagen into the middle cerebral artery (MCA) reduces cerebral blood flow (CBF) in the rat. Laser-Doppler flowmetry was used to monitor CBF in the territory of the MCA before, during, and after occlusion of the MCA by injection of collagen or a preformed clot through a catheter threaded to the MCA orifice. “Base” represents stabilized CBF at baseline expressed as percent; “start” represents insertion of the clot or first collagen injection (total of 6 injections every 5 min); “reperfusion” represents removal of the catheter and release of the bilateral common carotid ligatures. N = 12 each group.