Table 3.

Episodes of intercurrent illness requiring additional hydrocortisone, over time.

	0–12 months (n = 71)	12–24 months (n = 68)	24–36 months (n = 68)	36–48 months (n = 67)	48–60 months (n = 67)	0–60 months (n = 71)
Intercurrent illness
Number of episodes	123	132	206	153	95	709
Number of patients with any episode	42	39	38	40	36	64
Number of days with episodes	520	651	473	661	256	2561
Number of episodes per patient
Mean (s.d.)	2.9 (3.9)	3.4 (5.1)	5.4 (16.7)	3.8 (9.6)	2.6 (3.4)	11.1 (23.8)
Median (range)	2.0 (1−20)	2.0 (1−31)	2.0 (1−104)	1.0 (1−61)	1.5 (1−181)	6.0 (1−169)
Number of days per episode
Mean (s.d.)	6.5 (19.7)	8.3 (19.1)	3.8 (2.8)	9.1 (28.4)	2.6 (2.6)	4.7 (8.2)
Median (range)	2.8 (1−129)	2.7 (1−113)	3.0 (1−12)	3.0 (1−182)	2.0 (1−16)	2.6 (1−56)
Dose per episode (mg)
Mean (s.d.)	19.2 (11.4)	18.9 (12.1)	23.5 (13.9)	18.7 (8.9)	19.1 (13.1)	20.5 (11.2)
Median (range)	19.1 (5−60)	18.9 (5−60)	20.0 (5−68)	20.0 (5−40)	20.0 (5−60)	19.8 (5−60)

Mean values do not always consist of 0−60 month values because episodes of extra hydrocortisone use may have overlapped consecutive 12-month periods.