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. Author manuscript; available in PMC: 2018 Apr 15.
Published in final edited form as: Toxicol Lett. 2017 Mar 12;272:68–74. doi: 10.1016/j.toxlet.2017.03.008

Table 2.

Genes assayed for droplet digital PCR validation with microarray fold change (treated vs. control) in the distal uterus and Entrez Gene database information

Gene Fold change Gene name and associated function
Ccl6 −2.74094242 Chemokine (C-C motif) ligand 6 / cytokine activity, apoptosis
Clca4 −24.398129 Chloride channel accessory 4 / chloride transport
Clec4a3 −2.82542789 C-type lectin domain family 4, member A3 / may play a role in immune response, phagocytosis
Clec7a −2.18258692 C-type lectin domain family 7, member A / pathogen recognition, regulated by Esr1
Ctse −3.81489471 Cathepsin E / antigen processing, regulates Il18
Dmbt1 −7.61495061 Deleted in malignant brain tumors 1 / associated with endometrioid cancer, role in interaction of tumor cells and immune system
Ecm1 −1.9850104 Extracellular matrix protein 1 / angiogenesis, inflammatory response
Fcgr1a −2.22506708 Fc fragment of IgG, high affinity Ia, receptor (CD64) / immune response, antigen presentation
Fcgr3a −3.81127061 Fc fragment of IgG, low affinity IIIa, receptor (CD16) / immune response regulation
Iapp −4.37469083 Islet amyloid polypeptide / apoptosis
Il18 −2.14066052 Interleukin 18 / cytokine activity, T cell activation
RT1-DMb −2.03443864 RT1 class II, locus DMb / may play a role in antigen presentation
Tlr4 −2.04418908 Toll-like receptor 4 / innate immunity activation, pathogen recognition