Figure 3.

Body composition of Igfbp4^−/− mice. DXA analysis of Igfpb4^−/− mice measured at 8 and 16 weeks of age. (A) Fat proportion is calculated as the percent of fat within the entire body of the animal excluding the head. (B) Lean mass is estimated as the total tissue mass without the fat mass. (C and D) Bone parameters were measured in the entire body excluding the head. aBMC, areal bone mineral content; aBMD, areal bone mineral density. (n = 10/genotype/gender, *t-test P value <0.05, **t-test P value <0.01.)