Figure 4.

Alterations of the femoral architecture of Igfbp4^−/− mice. μCT analysis of femurs from 16-week-old animals was performed using VivaCt-40. (A, B, C, D and F) Trabecular parameters and representative pictures of trabecular bone. (G, H and I) Cortical measurements and representative pictures of cortical bone. BV/TV, bone volume/total volume; Ct.A/TA, cortical area/total area. (n = 8–10/genotype/gender, *t-test P value <0.05, **t-test P value <0.01.)