Table 1.
Demographic details of study participants
| COPD (n = 93) | S (n = 29) | HNS (n = 39) | COPD (n = 12) IHC/IF | S (n = 9) IHC/IF | NS (n = 6) IHC/IF | |
|---|---|---|---|---|---|---|
| Age | 66 (7) | 54.4 (7) | 41.6 (15.8) | 66.3 (4.6) | 66.3 (6.6) | 70 (5.7) |
| Gender (F:M) | 37:58 | 14:15 | 14:25 | 4:8 | 4:5 | 4:2 |
| Current smoker (n) | 35 | 26 | 0 | 9 | 9 | 0 |
| FEV1% predicted | 60.2 (18.9) | 98.1 (14.1) | 109.6 (14.4) | 67.3 (25.6) | 91 (11.9) | 108 (7.2) |
| FEV1/FVC (%) | 52 (12.5) | 75.5 (2.9) | 82.5 (6.9) | 67.3 (25.6) | 91 (11.9) | 108 (7.2) |
| GOLD I (%) | 18.3 | - | - | 33.3 | - | - |
| GOLD II (%) | 50.5 | - | - | 25 | - | - |
| GOLD III (%) | 26.9 | - | - | 41.7 | - | - |
| GOLD IV (%) | 4.3 | - | - | 0 | - | - |
| CAT | 17.1 (7.8) | |||||
| SGRQ | 39.4 (20.3) | |||||
| Smoking history (Pack Years)a | 37 (13-122) | 30.5 (12-67) | 0 | 42 (13-126) | 50 (21-66) | |
| ICS (%) | 65 | - | - |
This table shows the grouped demographic details of subjects who participated MSD plasma cytokine analysis, flow cytometric (FACS) & qPCR, chemotaxis (displayed on the left); lung immunohistochemistry/immunofluorescence (displayed on the right). Data is described by mean (SD). aData shown as median (range) Abbreviations: FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, CAT COPD Assessment Test and SGRQ St George’s Respiratory Questionnaire, ICS inhaled corticosteroid, IHC Immunohistochemistry, IF Immunofluorescence, NS non smoker