Table 2.
Marginated CX3CR1+ cells per unit vessel circumference
| COPD (n = 9) | S (n = 9) | NS (n = 6) | p value | |
|---|---|---|---|---|
| Vessel circumference (μm) | 722 (206.9) | 902 (275.2) | 766 (227.2) | ns |
| Marginated cells/vessel circumference (10-4/μm) | 10 (8) | 9 (9) | 20 (20) | ns |
| Marginated CX3CR1+ (%) | 3.1 (0-35.8) | 48.3 (10-73.7) | 85.8 (50-100) | 0.0002 |
| CX3CR1+/vessel circumference (10-4/μm) | 1 (0-80) | 30 (5-200) | 100 (20-1000) | 0.005 |
| CX3CR1+CD14+(Marginated CX3CR1+ cells %) | 0 (0-3.6) | 26.7 (0-49.2) | 73.4 (6.7-93.8) | 0.0008 |
| CX3CR1+CD14+/vessel circumference (10-4/μm) | 0 (0-3) | 20 (0-100) | 50 (2-400) | 0.002 |
| CX3CR1+CD16+(Marginated CX3CR1+ cells %) | 0 (0-29.3) | 17.3 (0-60.4) | 43 (20-69.9) | 0.001 |
| CX3CR1+CD16+/vessel circumference (10-4/μm) | 0 (0-100) | 10 (0-100) | 100 (10-400) | 0.02 |
This table shows CX3CR1+ cells as a percentage of all marginated cells as well the absolute number of CX3CR1+ cells per μm of vessel circumference (*10-4/μm). Data is displayed as median (range). The statistical significance of differences observed was obtained using Kruskal-Wallis test with application of Dunn’s multiple comparisons test. Vessel circumference and marginated cells/μm vessel circumference are displayed as mean (SD); the statistical significance of differences observed was assessed using ANOVA with application of Tukey’s post-test