Table 1.
Characteristics of the study population at enrolment (Numbers and percentages; medians and interquartile ranges (IQR))
| HN001 (n 212) | Placebo (n 211) | |||
|---|---|---|---|---|
| % | n | % | n | |
| Previous pregnancy | 67·5 | 143/212 | 73·8 | 155/210 |
| Diabetes in first-degree relative | 17·9 | 38/212 | 18·5 | 39/211 |
| Previous polycystic ovary syndrome | 8·1 | 17/209 | 10·6 | 22/208 |
| Age (years) | n 212 | n 210 | ||
| Median | 34 | 34 | ||
| IQR | 30–36 | 31–37 | ||
| Weight (kg) | n 211 | n 210 | ||
| Median | 69 | 71 | ||
| IQR | 63–80 | 63–82 | ||
| Waist circumference (cm) | n 211 | n 210 | ||
| Median | 87 | 87 | ||
| IQR | 80–94 | 81–99 | ||
| BMI (kg/m2) | n 211 | n 210 | ||
| Median | 25 | 26 | ||
| IQR | 23–29 | 23–30 | ||
| Ethnicity | 212 | 211 | ||
| Maori | 10·9 | 23 | 16·6 | 35 |
| Pacific | 3·8 | 8 | 1·9 | 4 |
| Asian | 7·7 | 15 | 7·6 | 16 |
| European | 78·3 | 166 | 73·5 | 155 |
| Other | 0·0 | 0 | 0·5 | 1 |
| Systemic antibiotic use during pregnancy before enrolment | 12·4 | 25/201 | 13·9 | 28/202 |
| Smoking | 5·2 | 11 | 3·8 | 8 |
| Systemic corticosteroid use | 1·4 | 3 | 1·4 | 3 |
| Treated asthma, eczema or hayfever | 87·3 | 185 | 82·9 | 175 |
| Household income (NZ$) | 207 | 204 | ||
| 0–49 000 | 8·2 | 17 | 7·8 | 16 |
| 50–99 000 | 30·4 | 63 | 32·4 | 66 |
| 100–149 000 | 35·8 | 74 | 34·8 | 71 |
| 150 000+ | 25·6 | 53 | 25·0 | 51 |
| Previous gestational diabetes | 5·0 | 6/121 | 7·1 | 9/127 |
| Weight of previous largest baby (g) | n 119 | n 124 | ||
| Median | 3520 | 3547 | ||
| IQR | 3260–3900 | 3232–3856 | ||
| Macrosomia (previous largest baby≥4000 g) | 20·2 | 24/119 | 14·5 | 18/124 |
HN001, Lactobacillus rhamnosus HN001.