Table 2. Description of the eight relevant Apnea Patients Network (APN) phenotypes.

The phenotypes (Ph) are listed with a short description in terms of most or least predominant AHI risk groups (low risk- L, mild- Mi, moderate- Mo, and severe- Se), significant combinations of the 6 objective parameters, and most/least predominant comorbidity types (cardiovascular- C, nutritional- N, respiratory- R, and without comorbidities- H) or comorbidity types overlaps (C + N, cardiovascular + nutritional; C + R, cardiovascular + respiratory, N + R, nutritional + respiratory; C + N + R, cardiovascular + nutritional + respiratory). For each phenotype, we provide the corresponding percentages for comorbidity types and comorbidity type associations, as well as the percentage of patients pertaining to one of the AHI risk groups; the boldface entries correspond to representative values, in terms of simple majority. In phenotype descriptions, HBP stands for high blood pressure.

Ph.	Description	Comorbidity types and associations (%)								AHI risk groups (%)
		C	N	R	C + N	C + R	N + R	C + N + R	H	L	Mi	Mo	Se
1	Mostly Se with C + N + R comorbidities	2.38	–	–	32.65	3.4	–	61.57	–	4	5	17	74
2	Mostly Mo and Se, thick neck females, no R, few N	6.49	0.65	–	61.04	3.9	0.65	27.27	–	9	15	19	57
3	Mostly Mo, Se, thin neck females, no R	13.66	10.24	–	48.29	1.95	2.93	22.93	–	12	13	31	44
4	Mostly Mo and Se, elderly males with thick neck, few R	6.52	3.62	–	36.96	5.8	3.62	44.48	–	4	4	20	72
5	Mostly Mi, Mo, Se, obese young males, mostly N	2.47	18.52	1.23	19.75	3.09	20.99	32.72	1.23	9	10	22	59
6	Mostly Mo, Se, 40–60 yrs. obese males, no HBP, mostly N	2.58	33.55	5.81	10.97	1.29	31.61	7.74	6.45	7	16	19	58
7	Less Se, non-obese, thin neck, no HBP males, mostly H, some R	8.84	0.68	27.21	0.68	4.76	–	–	57.83	13	22	25	40
8	Less Se, non-obese, thin neck, HBP males, mostly C	38.79	2.59	–	9.48	28.45	2.59	18.1	–	8	16	18	58