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. 2017 Apr 13;215(7):1124–1131. doi: 10.1093/infdis/jix071

Figure 1.

Figure 1.

SA-13, SA-15, and SA-17 neutralize LukAB-mediated cytotoxicity on primary human neutrophils. Monoclonal antibodies (mAbs) were preincubated with LukAB at indicated molar ratios for 30 minutes at room temperature. Primary human neutrophils (n = 6 donors) were added to the LukAB–mAb mixture and incubated for 1 hour. Neutrophil viability was evaluated with CellTiter and plotted as the mean ± SEM of percentage of dead cells. *P < .05 using 2-way analysis of variance with Tukey’s post hoc test correction for multiple comparisons. Each mean compared with immunoglobulin G control for statistical analysis. Abbreviations: IgG, immunoglobulin G; mAb, monoclonal antibody.