Table 2.
Univariate analysis of prognostic factors of overall survival
| Variables | Case (n) | Survival rate (%)
|
P-value | ||
|---|---|---|---|---|---|
| 1 year | 3 years | 5 years | |||
| Sex | 0.606 | ||||
| Male | 73 | 52.9 | 34.1 | 14.1 | |
| Female | 40 | 47.7 | 34.1 | 11.4 | |
| Age* | 0.384 | ||||
| <60 | 61 | 54.1 | 39.3 | 14.8 | |
| ≥60 | 68 | 48.5 | 29.4 | 11.8 | |
| Histology | 0.039 | ||||
| SCCE | 86 | 44.2 | 29.1 | 9.3 | |
| With squamous cell carcinoma | 43 | 65.1 | 44.2 | 20.9 | |
| Tumor stage | <0.001 | ||||
| T1 | 31 | 83.9 | 54.8 | 32.3 | |
| T2 | 37 | 51.4 | 35.1 | 10.8 | |
| T3 | 61 | 34.4 | 23.0 | 4.9 | |
| Tumor location | 0.026 | ||||
| Upper | 6 | 16.7 | 16.7 | 0 | |
| Middle | 104 | 56.7 | 38.5 | 15.4 | |
| Lower | 19 | 31.6 | 15.8 | 5.3 | |
| Nodal metastasis | <0.001 | ||||
| N0 | 84 | 65.5 | 45.2 | 17.9 | |
| N1 | 34 | 29.4 | 14.7 | 5.9 | |
| N2 | 9 | 11.1 | 11.1 | 0 | |
| N3 | 2 | 0 | 0 | 0 | |
| TNM stage | <0.001 | ||||
| I | 48 | 81.2 | 54.2 | 25.0 | |
| II | 54 | 42.6 | 29.6 | 9.3 | |
| III | 27 | 14.8 | 7.4 | 0 | |
| Perineural invasion | 0.687 | ||||
| Negative | 123 | 51.2 | 34.1 | 13.0 | |
| Positive | 6 | 50.0 | 33.3 | 16.7 | |
| Vessel involvement | 0.572 | ||||
| Negative | 127 | 50.4 | 34.6 | 13.4 | |
| Positive | 2 | 100 | 0 | 0 | |
| Adjuvant therapy | <0.001 | ||||
| Chemotherapy | 80 | 67.5 | 46.3 | 18.7 | |
| Radiochemotherapy | 49 | 24.5 | 14.3 | 4.1 | |
| NLR | 0.002 | ||||
| Low | 56 | 57.1 | 50.0 | 23.2 | |
| High | 73 | 46.6 | 21.9 | 5.5 | |
Note:
*
Mean age.
Abbreviations: NLR, neutrophil/lymphocyte ratio; SCCE, small-cell carcinoma of the esophagus.