Table 1.

Profile of symptoms, baseline clinical signs, and treatments

No	Age (years)	Sex	Symptoms	Baseline refractive value (D)	Baseline range of accommodation (D)	Baseline DE signs			Previously administered treatments	Additional treatments	Follow-up period (days)
						Schirmer (mm)	BUT (second)	ST (score)
1	56	Female	Eye dryness	0.19	−1.66	6	3	0	Sodium hyaluronate solution	Diquafosol tetrasodium instillation, DE moisture glasses	63
2	26	Female	Eye dryness, ocular fatigue	2.56	−2.54	15	0	1	Sodium hyaluronate and diquafosol tetrasodium solution	Lacrimal punctal plugs at superior and inferior puncta, DE moisture glasses	63
3	40	Female	Smarting, eye pain	3.33	−1.75	6	0	0	Sodium hyaluronate solution	Diquafosol tetrasodium solution	42
4	42	Female	Eye dryness	2.24	−1.48	6	0	0	Sodium hyaluronate and rebamipide solution	Thermosensitive atelocollagen punctal plug (Keeptear®)	56
5	60	Female	Eye dryness, ocular fatigue	0.59	−1.21	9	3	0	Sodium hyaluronate, rebamipide, and flavin adenine dinucleotide sodium solution	Diquafosol tetrasodium solution, lacrimal punctal plugs	94
6	36	Female	Eye dryness, eye pain	0.86	−4.68	10	4	0	Sodium hyaluronate, rebamipide, and flavin adenine dinucleotide sodium solution	Diquafosol tetrasodium solution, lacrimal punctal plugs	70
7	34	Female	Eye dryness, eye pain	2.84	−1.18	6	2	0	Sodium hyaluronate, diquafosol tetrasodium, and rebamipide solution	Lid hygiene, lacrimal punctal plugs	49
8	72	Male	Blurred vision, ocular fatigue	0.77	−0.59	6	1	0	–	DE moisture glasses	63
9	77	Male	Foreign body sensation, blurred vision	0.94	0.35	7	3	0	Diquafosol tetrasodium solution	Sodium hyaluronate, lacrimal punctal plugs	49
10	63	Male	Eye dryness, ocular fatigue	0.45	−3.02	8	0	0	–	Hyaluronic acid and diquafosol tetrasodium solution	35
11	23	Male	Blurred vision, dazzling sensation	2.02	−0.29	11	2	2	–	Hyaluronic acid and diquafosol tetrasodium solution	42
12	66	Female	Eye dryness, foreign body sensation	0.69	−6.59	8	5	0	Sodium hyaluronate solution	Diquafosol tetrasodium instillation	56

Abbreviations: BUT, break up time; DE, dry eye; ST, staining.