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. 2015 Oct 16;6:8651. doi: 10.1038/ncomms9651

Figure 1. SETDB1 is overexpressed in liver cancers.

Figure 1

(a) Publically available clinical cancer gene expression data (GSE6764) were downloaded from GEO to assess SETDB1 expression in HCC tumour samples. The expression of SETDB1 was extracted and box-plotted using Prism. (b) Total RNA was isolated from six pairs of human primary HCC tissues. The expression of SETDB1 in these samples was analysed using RT–qPCR. Data are presented as mean±s.d. (c) Representative immunohistochemical staining of the SETDB1 protein using HCC TMA. The sections were counterstained with haematoxylin and eosin (H&E) staining. Scale bar, 100 μM. (d) Percentages of strong positive, positive, weak positive and negative samples for SETDB1 in tumours (n=59) and normal adjacent controls (n=35).