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. 2017 Apr 19;17(4):898. doi: 10.3390/s17040898

Table 1.

Advantages and disadvantages of some recognition molecules in sensors.

Recognition Molecule Sensor Identification Advantages Disadvantages
Enzyme Enzymatic sensor
  • -

    Specificity

  • -

    Basic equipment and procedures
  • -

    High cost and time-wasting purification

  • -

    Low stability

  • -

    Efficiency only at an optimum pH and temperature
Antibody Immunosensor
  • -

    Extreme affinity

  • -

    Specificity
  • -

    Minimal target

  • -

    Hard production

  • -

    Use of animals requirement

  • -

    Stability deficiency
Nucleic acid Genosensor
  • -

    Stability
  • -

    Minimal target
Cell Cell sensor
  • -

    Low cost preparation

  • -

    Low purification needs
Aptamer Aptasensor
  • -

    Easy to modify

  • -

    Possibility of structure design

  • -

    Possibility of denaturalization and rehybridization

  • -

    Possibility of distinguishing targets

  • -

    Thermal stability

  • -

    In-vitro synthesis
MIPs MIP sensor
  • -

    Extreme thermal, chemical and mechanical resistance

  • Reusability
  • -

    Complicated fabrication methods

  • -

    Time-wasting procedure

  • -

    Incompatibility with aqueous solutions

  • -

    Template release

  • -

    Lower specificity