Table 3.
Comparison of the sensor studies for antibody and antigen detection.
| Parameters | Reference | ||||||
|---|---|---|---|---|---|---|---|
| [65] | [92] | [93] | [94] | [95] | [96] | [97] | |
| Target | Fab fragment | Cyclic citrullinated peptide antibody | Hepatitis B surface antibody | Prostate specific antigen | Prostate specific antigen | Vancomycin | Immunoglobulin G |
| Linear dynamic range | 2–15 mg/mL | 1–200 RU/mL | 0–120 mIU/mL | 0.1–50 ng/mL | 0.29–5000 ng/mL | 0.001–70 nM | 0.05–2.0 mg/mL |
| Buffers (Ads, Des) | pH 7.4, 1 M NaCl | pH 7.0, Acetic acid with Tween 20 | NA, 1 M Ethylene glycol | pH 7.4, Glycine HCl (pH 2.5) | PBS, 100 mM HCl | PBS (pH 7.4), NA | pH 7.4, 1 M NaCl |
| Time | 40 min | 40 min | 40 min | 50 min | 53 min | NA | 52 min |
| Limit of detection | 56 ng/mL | 0.177 RU/mL | 208.2 mIU/mL | 91 pg/mL | 0.29 ng/mL | 2.5 pM | NA |
NA: not available.