Table 6.
Characteristics of the individual FKBP5 methylation factor 2 CpGs and β and p-value of the FKBP5 rs1360780 x FKBP5 CpG beta value x resistant behavior in a regression analysis of the associations between FKBP5 rs1360780, FKBP5 CpG, and resistant behavior on cortisol reactivity during the Strange Situation Procedure
Three-way interaction values with cortisol reactivity |
||||
---|---|---|---|---|
CpG | mean beta value (SD) | Factor 2 loadings | β | p-value |
cg07633853 | .33 (.07) | 0.63 | .05 | .313 |
cg14284211 | .26 (.06) | 0.90 | .14 | .006 |
cg03591753 | .55 (.03) | 0.66 | .11 | .036 |
cg15929276 | .13 (.04) | 0.47 | .13 | .008 |
cg23416081 | .27 (.05) | 0.86 | .11 | .033 |
Note. FKBP5 rs1360780: CC = 0, CT = 1, TT = 2. Analyses are adjusted for technical methylation covariates, cell type proportions of DNA methylation sample, infant age at assessment of SSP, infant gender, educational level of the mother and maternal smoking during pregnancy. The statistics are derived from the final block of the regression model.