Table 7. 5α-reductase 2 expression in 8-, 12-, 16-, and 20-week-old C57BL/6 TRAMP x FVB mice.
The values are the mean total 5α-reductase 2 probe copies per tissue area (μm2) ± SEM in prostate epithelium, hyperplasia or tumor.
| 5α-reductase 2 | ||||||
|---|---|---|---|---|---|---|
| Group | n | Prostate epithelium | n | Hyperplasia | n | Tumor |
| 8-weeks | 5 | 9.0 ± 4.7 | 5 | 3.8 ± 1.3 | - | — |
| 12-weeks | 5 | 12.2 ± 5.3 | 5 | 9.0 ± 4.6 | 2 | 12.7 ± 10.6 |
| 16-weeks | 4 | 7.5 ± 2.6 | 4 | 6.9 ± 3.6 | 2 | 0.7 |
| 20-weeks | 1 | 17.7 | 1 | 1.8 | 3 | 4.1 ± 1.6 |
p < 0.05 vs. prostate epithelium, hyperplasia and tumor within and between groups. Data are multiplied by 1000.