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TRs bind to M-protein promoter. A, Sequence of the proximal M-protein is shown (−250 to −50); top right shows the consensus TRE sequence used to search for putative TREs, which are indicated by underlining the sequences. B, Fragments of M-protein (−239/−56) and GH (−200 /−165) promoters were amplified from DNA extracted from the input and ChIP originated from each sample. Values from the amplification of each ChIP sample were normalized by the respective input. AB, antibody.
