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. 2013 Nov 21;28(1):138–150. doi: 10.1210/me.2013-1186

Figure 2.

Figure 2.

Effects of PPP and NVP-AEW541 on the expression of kitlga in cultured zebrafish follicle cells. A and B, Dose response of PPP and NVP-AEW541 effects on the expression of kitlga in cultured zebrafish follicle cells after 6 hours of treatment. The data were normalized to the housekeeping gene ef1a and expressed as the percentage of the control group (mean ± SEM; n = 4). ***, P < .001 vs control. C and D, Effects of IGF-I on the expression of kitlga in the presence of PPP or NVP-AEW541 in cultured zebrafish follicle cells. Cultured zebrafish follicle cells were pretreated with PPP (10 μM) or NVP-AEW541 (2 μM) for 30 minutes before treatment with IGF-I (50 ng/mL) for 6 hours. The data are normalized to the housekeeping gene ef1a and expressed as the percentage of the control group (mean ± SEM; n = 4). Different letters indicate statistical significance (P < .05).