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. 2017 May 11;12(5):e0177269. doi: 10.1371/journal.pone.0177269

Fig 2. Fructooligosaccharides (FOS) or dead L. salivarius feeding decreased the intestinal bacterial overgrowth in STZ-DM mice.

Fig 2

(A) Relative abundance of bacteria across difference groups, as indicated by 16S rRNA gene sequencing. Values represent the mean abundance of Genus found at >1% relative abundance in at least one sample. (B) The collected mucosa from the terminal ileum were weighed and homogenized. Total bacteria counts were significantly increased in STZ-DM mice and FOS or dead L. salivarius feeding decreased them. (C) E. coli and K. pneumoniae of intestinal lumen were significantly increased in STZ-DM mice in comparison with those in SPF WT mice. FOS or dead L. salivarius feeding decreased the growth of pathogenic bacteria such as E. coli and K. pneumoniae in STZ mice. (D) The growth of lactobacilli/bifidas in intestinal lumen was significantly decreased in STZ-DM mice compared with SPF mice. FOS feeding significantly increased them in STZ-DM mice. STZ, streptozotocin; DM, diabetes mellitus; FOS, fructooligosaccharides; dLac, dead L. salivarius. *P<0.05, **P<0.01. n = 5/group.