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. 2017 May 11;12(5):e0177315. doi: 10.1371/journal.pone.0177315

Fig 8. Post-ischemic ROS production is reduced in female hearts.

Fig 8

Hydrogen peroxide production was assessed using Amplex Red in post-ischemic heart tissue and with purified α-ketoglutarate dehydrogenase. (A) Hydrogen peroxide production over time (male: open circles, female: closed circles) and (B) the rate of hydrogen peroxide production in post-ischemic male and female hearts (male: clear bar, female: black bar; n = 5 hearts/group; *p<0.05 vs. male). (C) Hydrogen peroxide production over time (control: open circles, GSNO: closed circles) and (D) the rate of hydrogen peroxide production with purified α-ketoglutarate dehydrogenase treated with and without GSNO (control: clear bar, GSNO: black bar; n = 6 replicates/group; *p<0.05 vs. control).