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. 2017 May 11;12(5):e0177315. doi: 10.1371/journal.pone.0177315

Table 3. Common SNO protein identifications resulting from different cardioprotective interventions.

Protein Name Protein ID SNO Cysteine
Male
Baseline
Female
Baseline
Male
CHA
Female
CHA
Male [3]
IPC
Male [4]
PostC
Aconitase Q99KI0 385 385 385 385 385 385
Aspartate aminotransferase, mitochondrial P05202 295 295 ND 295 295 295
Cytochrome b-c1 complex subunit 1, mitochondrial Q9CZ13 268, 380 268, 380 268, 380 268, 380 268, 380 380
Electron transfer flavoprotein subunit alpha, mitochondrial Q99LC5 53, 155 53, 155 ND 155 155 ND
Electron transfer flavoprotein subunit beta, mitochondrial Q9DCW4 71 71 71 71 66, 71 ND
Enoyl-CoA hydratase, mitochondrial Q8BH95 225 111, 225 111, 225 111, 225 225 111, 225
Fructose-bisphosphate aldolase A P05064 339 339 339 339 339 339
Glyceraldehyde-3-phosphate dehydrogenase P16858 150, 154, 245 150, 154, 245 150, 154, 245 150, 154, 245 150, 154, 245 150, 154, 245
Isocitrate dehydrogenase [NAD] subunit alpha Q9D6R2 ND ND 359 359 331 331
Isocitrate dehydrogenase [NADP], mitochondrial P54071 113, 402 113, 402 ND 113, 402 308, 402 308, 402
L-lactate dehydrogenase A chain P06151 84, 163 84, 163 84, 163 84, 163 84, 163 163
Malate dehydrogenase, cytoplasmic P14152 137, 154 137, 154 137 137, 154 137 ND
Malate dehydrogenase, mitochondrial P08249 89, 93, 275, 285 89, 93, 211, 275, 285 89, 93, 275 89, 93, 211, 275, 285 275 89, 275
Mitochondrial complex I-75 kDa Q91VD9 75, 92 75, 92 75, 92 92, 726 92 75
Myosin light chain 1 P09542 191 85, 191 ND 85, 191 ND ND
Propionyl CoA carboxylase alpha chain Q91ZA3 107 107 107 107 107 107
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 O55143 349, 364, 447, 471 344, 349, 364, 447, 471, 635, 669 364, 635 344, 364, 447, 635, 998 498 344, 349, 364
Serum albumin P07724 77, 289, 416, 500, 501 77, 289 77, 289 77, 289 ND ND
Succinate dehydrogenase [ubiquinone] flavoprotein, mitochondrial Q8K2B3 536 89, 536, 654 654 536, 654 536 654
Succinyl-CoA ligase alpha Q9WUM5 172, 181 172, 181 172, 181 172 60 172, 181
Succinyl-CoA ligase subunit beta, mitochondrial Q9Z2I9 430 152, 158, 270, 430 152, 158, 430 152, 158, 430 430 158, 430
Triosephosphate isomerase P17751 117, 268 117, 268 117, 268 117, 268 67, 218 117, 268
Voltage-dependent anion-selective channel protein 1 Q60932 245 245 245 245 245 245
Voltage-dependent anion-selective channel protein 2 Q60930 48 48 48 48 48 48

Common SNO protein identifications resulting from different cardioprotective interventions (i.e., ischemic pre- and post-conditioning). SNO proteins were identified in male and female hearts (as noted on the top of the table), using SNO-RAC in tandem with LC-MS/MS. ‘SNO cysteine’ represents the modified residue; ‘ND’ indicates that the protein was not identified in the given sample set.