. 2017 May 11;12(5):e0177437. doi: 10.1371/journal.pone.0177437

Table 3. Spindle characteristics for automatically and manually detected spindles by groups of experts and non-experts.

Stage	Standard	Amplitude(μV)	Frequency(Hz)	Duration(s)	Density
N2	EGS	48.72 ± 8.81	13.31 ± 0.49	0.83 ± 0.10	1.85 ± 0.10
	nEGS-all	45.14 ± 9.59^a	13.29 ± 0.49	0.80 ± 0.07^a	2.94 ± 0.99^a
	nEGS-1	46.06 ± 9.75^a ^b	13.29 ± 0.50	0.79 ± 0.07^a	2.65 ± 0.99^a ^b
	nEGS-05	39.27 ± 9.52^a ^b ^c	13.26 ± 0.52	0.68 ± 0.06^a ^b ^c	1.51 ± 0.66^b ^c
	AS1	46.21 ± 11.60^a ^d	13.19 ± 0.44^a ^b ^c	0.66 ± 0.05^a ^b ^c	3.27 ± 0.33^a ^c ^d
	AS2	47.68 ± 13.00^b ^c ^d ^e	13.38 ± 0.29^b ^d ^e	0.74 ± 0.05^a ^b ^c ^d ^e	2.18 ± 0.33^b ^c ^d ^e
	AS3	58.89 ± 13.42^a ^b ^c ^d ^e ^f	13.26 ± 0.41^f	1.25 ± 0.19^a ^b ^c ^d ^e ^f	0.86 ± 0.49^a ^b ^c ^d ^e ^f
	AS4	31.03 ± 8.37^a ^b ^c ^d ^e ^f ^g	13.37 ± 0.37^b ^c ^d ^e ^g	1.11 ± 0.06^a ^b ^c ^d ^e ^f ^g	9.61 ± 1.15^a ^b ^c ^d ^e ^f ^g
N3	EGS	47.78 ± 11.04	13.37 ± 0.51	0.69 ± 0.11	0.51 ± 0.45
	nEGS-all	41.48 ± 11.08^a	13.24 ± 0.47	0.69 ± 0.06	1.23 ± 0.87^a
	nEGS-1	43.59 ± 11.00^a ^b	13.25 ± 0.46	0.69 ± 0.06	0.83 ± 0.69^a ^b
	nEGS-05	37.29 ± 9.64^a ^b ^c	13.20 ± 0.54	0.64 ± 0.06^a ^b ^c	0.57 ± 0.41^b ^c
	AS1	38.87 ± 11.36^a ^b ^c ^d	13.23 ± 0.41^a	0.60 ± 0.04^a ^b ^c ^d	3.06 ± 0.34^a ^b ^c ^d
	AS2	40.11 ± 10.94^a ^c ^d ^e	13.37 ± 0.30^b ^e	0.68 ± 0.04^d ^e	1.92 ± 0.42^a ^b ^c ^d ^e
	AS3	54.95 ± 16.02^a ^b ^c ^d ^e ^f	13.36 ± 0.57^e	1.10 ± 0.19^a ^b ^c ^d ^e ^f	0.31 ± 0.21^a ^b ^c ^d ^e ^f
	AS4	27.09 ± 8.11^a ^b ^c ^d ^e ^f ^g	13.29 ± 0.36	1.11 ± 0.07^a ^b ^c ^d ^e ^f	9.91 ± 1.37^a ^b ^c ^d ^e ^f ^g

Data are presented as mean ± standard deviation unless otherwise indicated. The EGS was the expert group standard. The nEGS-all was the non-expert group standard with all spindles when both the weighted value of 1 and 0.5 were considered. The nEGS-1 was the non-expert group standard with definite spindles when the weighted value of 1 was only considered. The nEGS-05 was the non-expert group standard with indefinite spindles when the weighted value of 0.5 was only considered. The AS1, AS2, AS3 and AS4 were the automatic standards obtained by the first, second, third and fourth automated method, respectively.

^aIndicates significant difference from EGS.

^bIndicates significant difference from nEGS-all.

^cIndicates significant difference from nEGS-1.

^dIndicates significant difference from nEGS-05.

^eIndicates significant difference from AS1.

^fIndicates significant difference from AS2.

^gIndicates significant difference from AS3.