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. 2017 May 11;12(5):e0177080. doi: 10.1371/journal.pone.0177080

Table 1. The genotype and allele frequencies of identified SNPs in AS cases and healthy controls.

Gene SNP Genotype Case Control χ2 P Allele Case Control OR (95%CI) χ2 P
USP34 rs14170 A/A 268 309 5.346 0.069 A 810 861 1.202(1.015–1.423) 4.560 0.033
A/G 274 243 G 424 375
G/G 75 66
rs11428092 -/- 282 261 3.816 0.148 - 835 795 0.857(0.725–1.013) 3.285 0.070
-/A 271 273 A 397 441
A/A 63 84
rs10208769 A/A 279 310 3.026 0.220 A 823 861 1.147(0.968–1.358) 2.505 0.114
A/T 265 241 T 411 375
T/T 73 67
rs2123111 G/G 280 321 5.335 0.069 G 823 875 1.210(1.021–1.435) 4.829 0.028
G/A 263 233 A 411 361
A/A 74 64
FAM161A rs6545910 C/C 396 410 2.604 0.272 C 990 997 1.028(0.843–1.254) 0.075 0.784
C/T 198 177 T 244 239
T/T 23 31
rs6748320 G/G 246 266 1.175 0.556 G 779 806 1.085(0.920–1.280) 0.946 0.331
G/A 287 274 A 451 430
A/A 82 78
rs3736598 G/G 253 270 0.913 0.634 G 789 811 1.076(0.912–1.270) 0.761 0.383
G/A 283 271 A 445 425
A/A 81 77
AHSA2 rs777585 T/T 281 261 3.174 0.205 T 832 795 0.867(0.734–1.024) 2.834 0.092
T/C 270 273 C 400 441
C/C 65 84
B3GNT2 rs3811616 A/A 365 357 0.328 0.849 A 946 940 0.967(0.803–1.164) 0.127 0.722
A/G 216 226 G 288 296
G/G 36 35
C2orf74 rs1729674 T/T 266 303 4.490 0.106 T 803 853 1.195(1.011–1.414) 4.339 0.037
T/G 271 247 G 431 383
G/G 80 68
COMMD1 rs55785307 C/C 334 342 0.435 0.804 C 911 925 1.055(0.880–1.263) 0.332 0.564
C/G 243 241 G 323 311
G/G 40 35
KIAA1841 rs1177284 G/G 195 222 3.458 0.177 G 692 716 1.070(0.913–1.256) 0.701 0.403
G/A 302 272 A 538 520
A/A 118 124
__ rs10865331 G/G 178 216 10.084 0.006 G 628 710 1.303(1.111–1.526) 10.678 0.001a
G/A 272 278 A 606 526
A/A 167 124

SNP, Single nucleotide polymorphism

a P-value remained statistically significant after Bonferroni correction.