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. 2017 Apr 27;13(4):e1006751. doi: 10.1371/journal.pgen.1006751

Table 2. Phenotypic description of PNs in wild-type, Sema-1a LOF and rescue experiments in Figs 2 and 4 and S7 Fig.

Sema-1a-deficient
PNs with a phenotype
of dendritic
mis-targeting to the region close to
the VC1 glomerulus
type of PN
(emb/larval)a
conditions of
Sema-1a expression
total number (n) % of dendritic mis-targeting in close proximity of the VC1 glomerulus % of dendritic occupancy in Brp negative regions and/or partial glomerulus % of other dendritic mis-targeting notes
DC1 adPNe
(emb; Fig 2)
wt 5 0% 0% 20%d d some dendritic arbors around the D glomerulus
Sema-1aP1 3 100%b 0% 67%d b dendritic innervation to the region dorsal to the VC1 glomerulus
d dendritic innervation in the ventrolateral part of the DA3 glomerulus
DP1m adPN
(emb; Fig 4)
wt 24 0% 0% 17%d d a patch of dendritic arbors in the DM3 (9%) and DM1 (4%) glomeruli; heavy dendritic
innervation in both DP1m and VL2p glomerulus
Sema-1aP1 34 71%b 0% 62%d b dendritic innervation to the region around the VC1 glomerulus
d dendritic innervation in the DM3 glomerulus (56%) and the region lateral to the VM7
glomerulus (26%)
VL2p adPN
(emb; Fig 4)
wt 43 5%b 0% 9%d b a patch of dendritic arbors ventrally around the VC1 glomerulus
d some dendritic arbors posterior to DP1m, V or VL1 glomerulus or posterior to the AL
Sema-1aP1 15 87%b 0% 87%d b dendritic innervation mostly to the region posterior to the VC1 glomerulus (13% out of
87% without the SEZ innervation)
d dendritic innervation to the SEZ (13% out of 87% without the innervation around the
VC1 glomerulus)
DC2 adPN
(larval; Fig 4 & S7)
wt 5 0% 0% 40%d d a patch of dendritic arbors around the VA6 glomerulus
Sema-1aP1 21 45%b 0% 32%d b dendritic innervation mostly to the region dorsal to the VC1 glomerulus
d dendritic arbors around and/or within the VA6 glomerulus
Sema-1aP1+Sema-1a 5 0% 100%c 0% c dendritic innervation largely outside of the DC2 glomerulus (Brp negative region)
VA5 lPN
(larval; Fig 4 & S7)
wt 7 0% 0% 0%
Sema-1aP1 13 31%b 0% 23%d b dendritic innervation to the region ventral to the VC1 glomerulus
d dendritic innervation in part of the VA6 and/or DC3 glomeruli
Sema-1aP1+Sema-1a 8 0% 100%c 0% c dendritic innervation largely outside of the VA5 glomerulus (Brp negative region)
VA7m lPNe
(larval; Fig 4 & S7)
wt 4 0% 0% 25%d d a small patch of dendritic innervation to the VA4 glomerulus
Sema-1aP1 9 44%b 0% 67%d b dendritic innervation to the region close to the VC1 glomerulus
d dendritic innervation in part of the VA4 and/or VC2 glomeruli
Sema-1aP1+Sema-1a 15 0% 100%c 0% c dendritic innervation largely outside of the VA7m glomerulus (Brp negative region)
DA3/VC1 adPNe
(emb; Fig 4)
Sema-1aP1 2 100%b 0% 100%d b dendritic innervation to the region around the VC1 glomerulus
d heavy dendritic accumulation in the DA3 glomerulus

a emb:embryonic-born; larval: larval-born.

b, c, d see the description in the column of notes.

e same types of PNs can be also seen in different classes of dendritic mis-targeting phenotypes in Table 1 and S4 and S5 Tables.