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. Author manuscript; available in PMC: 2018 May 4.
Published in final edited form as: Cell. 2017 Apr 27;169(4):610–620.e14. doi: 10.1016/j.cell.2017.04.008

Figure 7. Model of ZIKV persistence in CSF and LN.

Figure 7

Schematic representation of the most relevant pathways and genes that were modulated by ZIKV and that correlated with persistent CSF and LN viral loads, highlighting increased inflammation, antiviral, cellular stress, and mTOR signaling pathways and decreased extracellular matrix and cell adhesion pathways. Interactions between genes and pathways were inferred from published literature. Red indicates activation; blue indicates inhibition.