Table 3.
W1‐2 | Rest Q1 | Q2 | Q3 | Q4 | Y2 | Y3 | Y4 | Y5 | Y6 | Adult (20–40 yo) | Imaging protocol | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Whole‐brain volume | ||||||||||||
Male individuals | 506 ± 96 | 609 ± 71 | 799 ± 130 | 922 ± 72 | 1,003 ± 99 | 1,192 ± 143 | 1,297 ± 179 | 1,347 ± 145 | 1,370 ± 62 | 1,383 ± 149 | Siemens 3T, 23 mm | |
Female individuals | 460 ± 22 | 575 ± 61 | 681 ± 161 | 908 ± 52 | 984 ± 93 | 1,040 ± 123 | 1,176 ± 110 | 1,244 ± 106 | 1,288 ± 124 | 1,328 ± 90 | ||
P values (male = female) | 0.23 | 0.22 | 0.15 | 0.37 | 0.37 | 0.002 | 0.029 | 0.048 | 0.025 | 0.12 | ||
Constructed atlases | 496 | 599 | 767 | 929 | 1,006 | 1,120 | 1,267 | 1,289 | 1,317 | 1,364 | ||
P values (population mean = atlas mean) | 0.52 | 0.52 | 0.70 | 0.79 | 0.65 | 0.52 | 0.75 | 0.33 | 0.44 | 0.62 | ||
Huang et al., 2006 | 367 ± 18 | 1,258 ± 86 | Phillips 1.5T, 1.83 mm | |||||||||
Knickmeyer et al., 2008 | 425 | 855 | 983 | Siemens 3T, 13 mm (T1) | ||||||||
Gilmore et al., 2007 (males) | 525 | Siemens 3T, 13 mm (T1) | ||||||||||
Gilmore et al., 2007 (females) | 487 | Siemens 3T, 13 mm (T1) | ||||||||||
Watanabe et al., 2013 (males) | ∼520 | ∼1,350 | ∼1,400 | Phillips 1.5T, 2 × 3 × 5 mm | ||||||||
Watanabe et al., 2013 (females) | 500 | ∼1,200 | ∼1,200 | Phillips 1.5T, 2 × 3 × 5 mm | ||||||||
Whole‐brain mean ADC | ||||||||||||
Male individuals | 1,377 ± 50 | 1,319 ± 177 | 1,163 ± 14 | 1,109 ± 21 | 1,067 ± 29 | 1,043 ± 42 | 1,003 ± 31 | 1,003 ± 26 | 978 ± 18 | 975 ± 26 | Siemens 3T, 23 mm | |
Female individuals | 1,467 ± 118 | 1,274 ± 58 | 1,204 ± 42 | 1,085 ± 29 | 1,069 ± 18 | 1,025 ± 35 | 1,011 ± 17 | 1,001 ± 23 | 976 ± 35 | 967 ± 36 | ||
P values (male = female) | 0.06 | 0.32 | 0.06 | 0.14 | 0.45 | 0.10 | 0.22 | 0.41 | 0.45 | 0.22 | ||
Constructed atlases | 1,385 | 1,290 | 1,202 | 1,096 | 1,068 | 1,039 | 1,006 | 1,001 | 974 | 968 | ||
P values (population mean = atlas mean) | 0.25 | 0.37 | 0.92 | 0.55 | 0.51 | 0.75 | 0.49 | 0.40 | 0.50 | 0.29 | ||
Watanabe et al | ∼1,220 | ∼860 | ∼760 | Phillips 1.5T, 2 × 3 × 5 mm |
Bold values indicate our result. The unit for b values is s/mm2. In the far right column, the imaging modality is diffusion imaging by default; modalities that are not diffusion imaging are noted in the bracket [e.g., (T1) means T1‐weighted MRI]. For diffusion imaging, b = 1,000 s/mm2 unless otherwise noted. Gray bars are results in our cohort (comparing males versus females, individuals versus atlases). P values indicating statistical significant differences (P < 0.05) are in italics.