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. 2017 Mar 4;17(2):265–278. doi: 10.1007/s40268-017-0176-x

Table 5.

BAT in immediate NMBA hypersensitivity

Stimulus Ref. test Activation marker Sensitivity (%) Specificity (%) N Ref.
Various NMBA H CD63
CD45
64
43
81
96
26 [123]
Various NMBA H + ST CD63 54 100 56 [12]
Various NMBA H CD63
CD203c
79
36
100
100
31 [124]
Various NMBA H + ST CD63 36–86a 93 92 [125]
Rocuronium H + ST CD63 92b 100 22 [71]
Various NMBA H + ST + IgE CD63 60 100 49 [126]
Rocuronium H CD63 80 96 104 [68]
Various NMBA H + ST CD63 68 100 56 [127]
Atracurium H + ST CD63 71c 100 75 [72]

BAT basophil activation test, H history, IgE immunoglobulin E, N number of patients and control individuals, NMBA neuromuscular blocking agent, Ref. reference, ST skin test

aIncreasing sensitivity when only the reactions that occurred during the 3 years were taken into account

bTaking into account the non-responders, sensitivity is 76%

cTaking into account the non-responders, sensitivity is 63%