Table 5.
Stimulus | Ref. test | Activation marker | Sensitivity (%) | Specificity (%) | N | Ref. |
---|---|---|---|---|---|---|
Various NMBA | H | CD63 CD45 |
64 43 |
81 96 |
26 | [123] |
Various NMBA | H + ST | CD63 | 54 | 100 | 56 | [12] |
Various NMBA | H | CD63 CD203c |
79 36 |
100 100 |
31 | [124] |
Various NMBA | H + ST | CD63 | 36–86a | 93 | 92 | [125] |
Rocuronium | H + ST | CD63 | 92b | 100 | 22 | [71] |
Various NMBA | H + ST + IgE | CD63 | 60 | 100 | 49 | [126] |
Rocuronium | H | CD63 | 80 | 96 | 104 | [68] |
Various NMBA | H + ST | CD63 | 68 | 100 | 56 | [127] |
Atracurium | H + ST | CD63 | 71c | 100 | 75 | [72] |
BAT basophil activation test, H history, IgE immunoglobulin E, N number of patients and control individuals, NMBA neuromuscular blocking agent, Ref. reference, ST skin test
aIncreasing sensitivity when only the reactions that occurred during the 3 years were taken into account
bTaking into account the non-responders, sensitivity is 76%
cTaking into account the non-responders, sensitivity is 63%