Figure 8.

Slc1a5^−/− B cells generate a functional germinal center (GC) response. (A) Representative gating strategy for hen egg lysozyme (HEL)-binding GC B cells in the spleen and representative flow cytometry dot plots for mice immunized with sheep red blood cells (SRBCs) that were either unconjugated (B) or conjugated to HEL (C). n = 8 mice injected with Slc1a5^+/+ CD45.1⁺ and Slc1a5^−/− CD45.1⁺/CD45.2⁺ SW_HEL B cells and SRBC-HEL. n = 2 Mock-SRBC control mice injected with Slc1a5^+/+ CD45.1⁺ and Slc1a5^−/− CD45.1⁺/CD45.2⁺ SW_HEL B cells and unconjugated SRBCs.