Classification of pancreatic tumors (WHO 2010 classification) |
Benign
|
Acinar cell cystadenoma |
Serous cystadenoma |
Premalignant lesions
|
Pancreatic intraepithelial neoplasia type 3 (PanIN-3) |
Intraductal papillary mucinous neoplasm with low or intermediate grade dysplasia |
Intraductal papillary mucinous neoplasms |
High-grade dysplasia |
Tubulo-papillary intraductal neoplasia |
Mucinous cystic dysplasia neoplasia with low or intermediate grade |
Mucinous cystic neoplasm with high-grade dysplasia |
Malignant
|
Ductal adenocarcinoma |
Adenosquamous carcinoma |
Colloid carcinoma (non-cystic mucinous carcinoma) |
Hepatoid carcinoma |
Medullary carcinoma |
Cell carcinoma signet ring |
Undifferentiated carcinoma |
Undifferentiated carcinoma with osteoclast-like giant cells |
Acinar cell carcinoma |
Cystoadenocarcinoma acinar cells |
Intraductal papillary mucinous neoplasm or associated with invasive carcinoma |
Mixed acinar-ductal carcinoma |
Mixed acinar-neuroendocrine carcinoma |
Mixed-neuroendocrine carcinoma acinar-ductal |
Mixed ductal-neuroendocrine carcinoma |
Mucinous cystic neoplasm associated with invasive carcinoma |
Pancreatoblastoma |
Serous cystoadenocarcinoma |
Pseudopapillary or solid neoplasia |
Neuroendocrine neoplasms |
Pancreatic neuroendocrine microadenoma |
Neuroendocrine tumor (NET) |
Pancreatic, not functioning G1, G2 NET |
G1 NET |
G2 NET |
Neuroendocrine carcinoma (NEC) |
Large cell NEC |
Small cell NEC |
NET serotonin producer (carcinoid) |
Gastrinoma |
Glucagonoma |
Insulinoma |
Somatostatinoma |
VIPoma |
Mature teratoma |
Mesenchymal tumors |
Lymphomas |
Metastasis |