Table 2.

Distribution of membrane staining results among primary tumors of renal cancer from patients treated for metastatic disease with sunitinib or sorafenib in first- or second-line setting

Intensity score	Percentage stained (%)	Number of cases
Intensity (circumference) of stained membrane and distribution
0	0–10	46
1	11–80	26
2	81–100	34

Fraction score	Percentage stained (%)	Number of cases
Fraction of stained membrane and distribution
0	0–1	55
1	2–25	20
2	26–50	21
3	51–75	5
4	76–100	5

Combined score	Number of cases
Combined score (addition of intensity and fraction score) and distribution
0	46
1	7
2	10
3	19
4	17
5	3
6	4

Cubilin expression	Number of cases
Cubilin negative and positive cases
(−)	53
(+)	53