Table 4.

Correlations between reported dose and extrapolated 4‐h plasma paracetamol concentrations, APAP_pl:APAP_t ratio, and markers of organ injury in patients receiving acetylcysteine within 8 h of overdose

	Peak serum aminotransferase concentration, IU l −1			Peak INR			Peak serum creatinine, μmol l −1
	r	95% CI	P	r	95% CI	P	r	95% CI	P
Reported dose, mg	0.153	0.025−0.276	0.02	−0.040	−0.167−0.089	0.53	0.108	−0.021−0.233	0.09
Extrapolated 4‐h plasma concentration, mg l −1	0.184	0.059−0.304	0.003	0.271	0.150−0.385	<0.0001	−0.029	−0.155−0.098	0.65
APAP pl :APAP t	0.185	0.060−0.305	0.003	0.269	0.232−0.391	<0.0001	−0.027	−0.153−0.100	0.67