[Table/Fig-7]:
Statistical correlation of imprint cytology, frozen section with histopathology.
| Parameter | Imprint cytology | Frozen section |
|---|---|---|
| Number of inadequate material | 1 | 0 |
| Number of benign lesions | 27 | 28 |
| Number of malignant lesions | 34 | 34 |
| Total Number of evaluated cases | 61 (98.39%) | 62 (100%) |
| Total benign lesions on histopathology - 29 | ||
| Total malignant lesions on histopathology -33 | ||
| True positive‡ | 33(97.06%) | 33 (97.06%) |
| False positive ‡ | 1 (2.94%) | 1 (2.94%) |
| True negative ‡ | 27 (100%) | 28 (100%) |
| False negative‡ | 0 | 0 |
| Sensitivity § | 100% | 100% |
| Specificity § | 96.43% | 96.55% |
| Positive predictive value § | 97.06% | 97.06% |
| Negative predictive value § | 100% | 100% |
| Diagnostic accuracy § | 98.36% | 98.39% |
| p-value | <0.001 | <0.001 |
Tests of significance: Criteria
‡A true-positive result for malignancy indicated that IC, FS and histopathological analysis of the specimen was diagnostic of a malignant lesion.
‡A false-positive result for malignancy indicated that a diagnosis of malignancy was given on IC and FS, but the HP turned out to be benign.
‡A true negative result was considered when the diagnosis on IC, FS and HP was benign.
‡A false-negative result was considered when IC and FS showed no malignancy but the final diagnosis turned out to be malignant on HP.
§Sensitivity: probability that a test result will be positive when the disease is present (true positive rate, expressed as a percentage); §Specificity: probability that a test result will be negative when the disease is not present (true negative rate, expressed as a percentage); § Positive predictive value: probability that the disease is present when the test is positive (expressed as a percentage); §Negative predictive value: probability that the disease is not present when the test is negative (expressed as a percentage); § Diagnostic Accuracy is the sum of true positive and True negative divided by number of cases (expressed as a percentage).