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. 2017 Mar 1;11(3):WC06–WC09. doi: 10.7860/JCDR/2017/23961.9550

[Table/Fig-9]:

Comparison between no. of patients developing side effects in each group.

Side effect Levocetirizine 5 mg Ebastine
20 mg
Ebastine
10 mg
p-value
Dryness Yes 47(31.3%) 23(15.3%) 20(13.3%) p<0.001
No 3(2%) 27(18%) 30(20%)
Sedation Yes 42(28%) 29(19.3%) 20(13.3%) p<0.001
No 8(5.3%) 21(14%) 30(20%)
Drowsiness Yes 42(35%) 21(14%) 12(8%) p<0.001
No 8(5.3%) 29(19.3%) 38(25.3%)
Headache Yes 27(18%) 10(6.6%) 8(5.3%) p<0.001
No 23(15.3%) 40(26.6%) 42(28%)

The difference in the number of patients experiencing side effects is varying for Ebastine 20mg, 10mg and Levocetirizine 5mg. This difference is highly significant (p<0.001) for all the side effects, for all three forms of medication.