Table 17.
Risk factor/trigger | Recommendations for clinical practice | Recommendations for research |
---|---|---|
Hyperthyroidism | Overt and subclinical hyperthyroidism increase AF risk Control thyroid function in patients at risk of AF Treat associated cardiovascular diseases and consider modification of risk factors |
More research is needed regarding risk factors and prevention of AF in populations with high-normal thyroid function (based on TSH level) and individuals with higher level of free thyroxin within normal range. |
Supraventricular tachyarrhythmias and paroxysmal AF | In patients with SVT and paroxysmal AF: Ablate SVT, continue antiarrhythmic drugs or ablate AF as needed. Checking for potential SVT substrate should be considered in patients with isolated PAF referred for ablation |
Additional studies on prevention of AF in patients with SVT are needed |
Post-operative AF | β-Blockers and amiodarone are indicated for prophylaxis of post-operative AF | More research is needed on use of pharmacological agents with anti-inflammatory and anti-remodelling properties, statins and other possible drugs for prevention of post-operative AF |
Upstream therapies | – | Investigation of the long term effects of sustained secondary prevention with upstream therapies starting before AF in people at risk and early after AF diagnosis are required |
AF, atrial fibrillation; PAF, paroxysmal atrial fibrillation; SVT, supraventricular tachycardia; TSH, thyroid stimulating hormone.