Table 4.

Adjusted odds ratio using fluid intake and fluid balance as design variables in multivariable logistic regression

Model 1				Model 2
Variables	Odds ratio	95% CI	P value	Variables	Odds ratio	95% CI	P value
Fluid intake level 1 (≤29)	Reference			Fluid balance level 1 (–19 ~ 0)	Reference
Level 2 (30 ~ 59)	0.73	0.56–0.96	0.024	Level 2 (–39 ~ –20)	0.88	0.69–1.11	0.286
Level 3 (60 ~ 89)	0.61	0.43–0.85	0.004	Level 3 (–59 ~ –40)	0.79	0. 65–1.11	0.181
Level 4 (>90)	0.47	0.30–0.74	0.001	Level 4 (≤ –60)	0.56	0. 33–0.95	0.034
Diuretics	1.36	1.09–1.68	0.005	Diuretics use	1.50	1.21–1.86	<0.001
Blood products	1.51	1.19–1.91	0.001	Blood product	1.36	1.08–1.72	0.009
Weight	0.98	0.98–0.99	<0.001	Weight	0.99	0.98–0.99	<0.001
Maximum WBC	1.03	1.02–1.05	<0.001	Maximum WBC	1.03	1.01–1.04	<.0001
Maximum SOFA score	1.11	1.08–1.14	<0.001	Maximum SOFA	1.11	1.07–1.13	<0.001
Maximum serum creatinine	1.15	1.08–1.22	<0.001	Maximum serum creatinine	1.18	1.11–1.26	<0.001
MICU	1.74	1.35–2.24	<0.001	MICU	1.89	1.48–2.42	<0.001
CCU	2.11	1.61–2.77	<0.001	CCU	2.29	1.75–2.99	<0.001

WBC white blood cells, SOFA sequential organ failure assessment, MICU medical ICU, CCU coronary care unit. Diuretic and blood product use was defined as any diuretics or blood products used within 48 hour of ICU admission while maximum serum creatinine and SOFA values are for the whole ICU stay. The mean variance inflation factor was 2.44 and 2.15 and the p value for goodness of fit was 0.258 and 0.372 in model 1and model 2, respectively