Table 4.
Genes identified by TIS in pEIB202 that affects maintenance or conjugation of pEIB202
| Loci | Gene | Product | Output/input a | P-value |
|---|---|---|---|---|
| ETAE_p001 | virD4 | T4SS component VirD4 | 0.015 | 0.000548801 |
| ETAE_p002 | virB11 | T4SS component VirB11 | 0.0058 | 0.000531746 |
| ETAE_p003 | virB10 | T4SS component VirB10 | 0.00099 | 0.000531259 |
| ETAE_p004 | hypothetical protein | 0.0022 | 0.000517762 | |
| ETAE_p005 | virB9 | T4SS component VirB9 | 0.0039 | 0.000520783 |
| ETAE_p006 | virB8 | T4SS component VirB8 | 0.0014 | 0.000530141 |
| ETAE_p007 | putative lipoprotein | 0.0034 | 0.000493853 | |
| ETAE_p008 | hypothetical protein | 0.10 | 0.0003746 | |
| ETAE_p009 | virB6 | T4SS component VirB6 | 0.011 | 0.000544597 |
| ETAE_p010 | putative lipoprotein | 0.18 | 1.61153E-05 | |
| ETAE_p011 | virB5 | T4SS component VirB5 | 0.0027 | 0.000535705 |
| ETAE_p012 | hypothetical protein | 0.026 | 0.0003982 | |
| ETAE_p013 | virB4 | T4SS component VirB4 | 0.0086 | 0.000541165 |
| ETAE_p014 | virB2 | T4SS component VirB2 | 0.019 | 0.000514194 |
| ETAE_p015 | hypothetical protein | 0.073 | 9.96994E-06 | |
| ETAE_p016 | topA | DNA topoisomerase | 4.30 | 0.000340276 |
| ETAE_p026 | transcriptional repressor protein | 0.020 | 6.77947E-06 | |
| ETAE_p047 | mobC | putative mobilisation protein | 0.13 | 0.000639706 |
| ETAE_p048 | virD2 | VirD2 component | 0.028 | 0.000545018 |
| ETAE_p053 | traC | DNA primase TraC4 | 0.15 | 2.38855E-05 |
aThe data indicate that the read number of a specific gene in output is significantly under-represented or over-represented as compared to that in input with a cutoff of less than 0.25 or higher than 4-fold and p < 0.001