Table 3.

Sensitivity and specificity for PTSD diagnosis across various cut-off scores of PCL-C

Cut-off Score	Sensitivity (95% CI)	Specificity (95% CI)	Youden index	+PV (95% CI)	-PV (95% CI)	+LR (95% CI)	-LR (95% CI)	PR
20	0.95 (0.90, 0.99)	0.23 (0.22, 0.25)	0.18	0.04 (0.03, 0.05)	0.99 (0.98, 1.00)	1.24 (1.19, 1.30)	0.20 (0.08, 0.47)	0.77
22	0.91 (0.84, 0.96)	0.41 (0.39, 0.43)	0.32	0.05 (0.04, 0.06)	0.99 (0.99, 1.00)	1.53 (1.44, 1.64)	0.22 (0.12, 0.41)	0.60
24	0.86 (0.78, 0.92)	0.54 (0.52, 0.55)	0.40	0.06 (0.05, 0.07)	0.99 (0.99, 1.00)	1.86 (1.70, 2.02)	0.26 (0.16, 0.42)	0.48
26	0.86 (0.78, 0.92)	0.63 (0.62, 0.65)	0.49	0.08 (0.06, 0.09)	0.99 (0.99, 1.00)	2.35 (2.16, 2.57)	0.22 (0.14, 0.35)	0.38
28	0.68 (0.58, 0.77)	0.70 (0.69, 0.72)	0.38	0.07 (0.06, 0.09)	0.99 (0.98, 0.99)	2.29 (1.99, 2.64)	0.46 (0.35, 0.60)	0.31
30	0.49 (0.39, 0.59)	0.76 (0.74, 0.77)	0.25	0.06 (0.05, 0.08)	0.98 (0.97, 0.98)	2.01 (1.64, 2.46)	0.67 (0.56, 0.81)	0.25
35	0.40 (0.31, 0.50)	0.87 (0.86, 0.88)	0.27	0.09 (0.07, 0.12)	0.98 (0.97, 0.98)	3.01 (2.35, 3.84)	0.69 (0.59, 0.81)	0.14
40	0.26 (0.18, 0.36)	0.91 (0.90, 0.92)	0.17	0.10 (0.06, 0.13)	0.97 (0.97, 0.98)	3.05 (2.19, 4.25)	0.81 (0.72, 0.90)	0.09
45	0.13 (0.07, 0.21)	0.95 (0.94, 0.95)	0.08	0.08 (0.04, 0.12)	0.97 (0.96, 0.98)	2.46 (1.48, 4.09)	0.92 (0.85, 0.99)	0.06

Abbreviations: +PV positive predicted value, −PV negative predicted value, +LR positive likelihood ratio, −LR negative likelihood ratio, PR prevalence; Bold text indicates the optimum cut-off