Table 1.
Baseline characteristics of study sample
| LifeLines sample adult populationa | Total sample present study population | Sample present study population in the correlation analyses | ||||
|---|---|---|---|---|---|---|
| N (%)b | N | N (%)b | N | N (%)b | N | |
| Age (years), mean (SD) | 45 (13.1) | 152180 | 53 (14.6) | 509 | 53 (14.5) | 471 |
| Gender (female) | 89050 (59%) | 152180 | 254 (50%) | 509 | 232 (49%) | 471 |
| Education level | 148679 | 507 | 469 | |||
| ≤ 12 years | 45439 (31%) | 120 (24%) | 106 (23%) | |||
| > 12 years | 103240 (69%) | 378 (76%) | 363 (77%) | |||
| Nationality | 151575 | 507 | 469 | |||
| Dutch | 143040 (94%) | 468 (92%) | 433 (92%) | |||
| Other | 8535 (6%) | 39 (8%) | 36 (8%) | |||
| Ruff Figural Fluency Test (RFFT)c | - | |||||
| Number of unique designs, mean (SD) | 85.16 (24.37) | 485 | 85.50 (24.18) | 471 | ||
| Error ratio, median (IQR) | 0.09 (0.05–0.15) | 485 | 0.09 (0.05–0.15) | 471 | ||
| CogStatec | - | |||||
| Groton Maze Learning (GMLT), median (IQR) | 52 (41–64) | 509 | 52 (41–64) | 471 | ||
| Groton Maze Learning– Delayed Recall (GMLR), median (IQR) | 7 (4–10) | 504 | 7 (4–10) | 471 | ||
| Detection (DET), mean (SD) | 2.57 (0.17) | 500 | 2.56 (0.17) | 471 | ||
| Identification (IDN), mean (SD) | 2.71 (0.09) | 507 | 2.70 (0.08) | 471 | ||
| One Back (OBK), mean (SD) | 1.32 (0.22) | 504 | 1.33 (0.20) | 471 | ||
| One Card Learning (OCL), mean (SD) | 0.97 (0.13) | 506 | 0.98 (0.13) | 471 | ||
| Marital status (in a relationship) | 150255 | 505 | 468 | |||
| Yes | 128493 (86%) | 403 (80%) | 374 (80%) | |||
| No | 21762 (14%) | 102 (20%) | 94 (20%) | |||
| Smoking status | 143245 | 500 | 462 | |||
| Never smoker | 68672 (48%) | 214 (43%) | 201 (43%) | |||
| Past smoker | 45350 (32%) | 207 (41%) | 189 (41%) | |||
| Current smoker | 29223 (20%) | 79 (16%) | 72 (16%) | |||
| Alcohol use | 136437 | 483 | 451 | |||
| No alcohol use | 29287 (21%) | 70 (15%) | 64 (14%) | |||
| Moderate alcohol use | 86613 (64%) | 343 (71%) | 324 (72%) | |||
| Problematic alcohol use | 20537 (15%) | 70 (14%) | 63 (14%) | |||
| Physical activityd | 138516 | 469 | 438 | |||
| Yes | 67240 (49%) | 250 (53%) | 237 (54%) | |||
| No | 71276 (51%) | 219 (47%) | 201 (46%) | |||
| Number of neurological disorderse | 150877 | 491 | 457 | |||
| No disease | 147564 (98%) | 476 (97%) | 444 (97%) | |||
| 1 disease | 3228 (2%) | 15 (3%) | 13 (3%) | |||
| 2 diseases | 85 (0.1%) | 0 (0%) | 0 (0%) | |||
| Number of cardiovascular disordersf | 111463 | 404 | 375 | |||
| No disease | 68921 (62%) | 235 (58%) | 218 (58%) | |||
| 1 disease | 33510 (30%) | 125 (31%) | 118 (32%) | |||
| 2 diseases | 8437 (8%) | 40 (10%) | 35 (9%) | |||
| ≥ 3 diseases | 595 (1%) | 4 (2%) | 4 (1%) | |||
| Depression (yes) | 7538 (6%) | 125987 | 33 (7%) | 495 | 33 (7%) | 460 |
| Diabetes (yes) | 3882 (3%) | 151786 | 27 (5%) | 507 | 25 (5%) | 469 |
aData available at the moment of data release of the present study; bThe percentage is reported, unless otherwise indicated; cIn the present study no data is available from the total LifeLines adult population; dComplies with the norm of at least thirty minutes of moderately intensive exercise at least 5 days a week; eStroke, multiple sclerosis, epilepsy; fMyocardial infarction, arrhythmia, heart failure, high blood pressure