Table 2.
Clinical characteristics, hormonal levels and sperm parameters of all men enrolled in the study stratified by the FSHB -211G/T genotype
| Parameter | FSHB -211G/T genotype | p value | ||
|---|---|---|---|---|
| GG | GT | TT | ||
| Age (years) | 32.1 ± 7.8 (31) | 32.5 ± 7.2 (31.5) | 27.2 ± 13.0 (22.5) | 0.732 |
| BMI (kg/m2) | 28.23 ± 4.5 (27.9) | 25.13 ± 5.18 (25) | 31 ± 4.5 (31) | 0.324 |
| Testicular volume (mL) | 28.25 ± 9.1 (28.3) | 28.7 ± 8.32 (26.6) | 21.7 ± 9.5 (21.8) | 0.573 |
| FSH (IU/L) | 6.9 ± 6.3 (4.6) | 3.76 ± 2.39 (3) | 2.27 ± 0.77 (2.15) | <0.001 |
| LH (IU/L) | 4.9 ± 2.3 (4.4) | 4.35 ± 2.14 (3.8) | 2.68 ± 0.8 (2.9) | 0.011 |
| Testosterone (nmol/L) | 5.18 ± 1.96 (5.0) | 4.87 ± 1.6 (4.9) | 3.6 ± 2.1 (3.5) | 0.095 |
| Sperm concentration (106/mL) | 38.9 ± 46.8 (21) | 34.01 ± 43.7 (10) | 18.4 ± 27.9 (6.8) | 0.432 |
| Total sperm count (×106/ejaculate) | 116 ± 162.9 (50) | 100 ± 124 (25) | 60 ± 93.8 (20) | 0.395 |
| Sperm forward motility (%) | 15.82 ± 11.0 (15) | 14.3 ± 12.6 (10) | 6.75 ± 8.95 (3.5) | 0.395 |
| Sperm with normal morphology (%) | 6 ± 4 (5) | 6.7 ± 6 (5) | 6.2 ± 4.7 (7.5) | 0.953 |
Data are expressed as mean ± SD and median in parentheses. Statistically significant levels are marked in italics (p < 0.05) or in bold for suggestive difference (p < 0.1)
BMI body mass index