a A 2PN zygote with a normal-sized pronucleus and a much smaller pronucleus (arrowhead) after polar body 2 transfer (PB2T). (b1, c1, d1, and e1) Day 3 embryos developing from the patient’s oocytes showed massive fragmentation, and the embryos reconstructed after PB1T of the four oocytes showed slight fragmentation on day 3 (b2, c2, d2, and e2) and developed to blastocyst stage (b3, c3, d3, and e3)