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. 2017 Apr 28;11:38–53. doi: 10.2174/1874104501711010038

Table 3.

Minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC) of the synthesized compounds 3-12 in µg/mL.

Cpd No. S. aureus B.subtilis P.aeruginosa E.coli C.albicans
MIC MBC MIC MBC MIC MBC MIC MBC MIC MBC
3a 100 100 50 100 100 100 100 200 50 100
3b 50 100 100 200 25 50 50 50 25 50
4 100 100 100 100 50 100 50 100 25 25
5 100 100 25 50 25 50 50 100 50 50
6 25 50 50 50 100 200 50 100 100 100
7a 100 200 100 100 50 100 100 100 50 100
7b 50 50 100 100 25 50 50 100 100 100
7c 100 200 25 50 100 100 25 50 100 100
9a 100 100 100 200 50 100 25 50 50 100
9b 50 50 100 100 50 100 50 100 50 50
10a 25 50 25 100 100 100 50 100 100 100
10b 50 100 100 200 25 50 100 100 25 50
10c 100 100 100 200 50 100 100 200 100 100
10d 100 100 100 100 50 50 25 50 50 100
10e 50 100 100 200 50 100 100 100 50 100
10f 100 200 50 100 100 100 25 50 100 200
11a 100 200 50 50 25 25 25 50 50 100
11b 100 100 100 100 25 100 25 25 50 100
12a 50 100 100 100 50 50 100 200 50 100
12b 100 100 100 100 50 100 25 25 50 100
Aa 5 - 12.5 - 50 - 10 - - -
Cb -c - - - - - 5 -

a A: Ampicillin trihydrate (standard broad spectrum antibiotic). bC: Clotrimazole (standard broad spectrum antifungal agent). c (–): Totally inactive (MIC > 200 µg/mL).