TABLE 1.
Demographic and Clinical Characteristics of HIV-Infected and HIV-Uninfected Subjects, Kaiser Permanente California, 1996–2011
| HIV-Infected | HIV-Uninfected | P | |
|---|---|---|---|
| N | 24,768 | 257,600 | |
| Person-years, total (mean/subject) | 122,032 (4.9) | 1,522,547 (5.9) | |
| Age at baseline, mean (SD) | 40.7 (10.1) | 40.2 (10.3) | <0.001 |
| Year of birth, mean (SD) | 1961 (11.1) | 1961 (11.4) | 0.20 |
| Gender, % | 0.76 | ||
| Men | 90.7 | 90.6 | |
| Women | 9.3 | 9.4 | |
| Race/ethnicity, % among known | <0.001 | ||
| White | 56.2 | 44.1 | |
| Hispanic | 21.0 | 27.3 | |
| Black | 17.8 | 10.4 | |
| Asian/Pacific Islander | 4.3 | 16.1 | |
| Other | 0.8 | 2.2 | |
| Ever history of tobacco smoking, % | 45.2 | 31.1 | <0.001 |
| Ever history of drug/alcohol abuse, % | 20.6 | 8.6 | <0.001 |
| Ever history of hepatitis B or C infection, % | 11.5 | 1.7 | <0.001 |
| HIV-transmission risk group, % among known | |||
| MSM | 74.7 | — | |
| Heterosexual sex | 16.3 | — | |
| IDU | 7.0 | — | |
| Other | 2.0 | — | |
| Years known to be HIV infected, mean (SD) | 3.8 (5.5) | — | |
| CD4 cells/μL at baseline, mean (SD) | 410 (290) | — | |
| Prior antiretroviral use, % | 45.6 | — | |
| Initiated ART during follow-up, % | 39.6 | — | |
| CD4 cells/μL at ART initiation, % | |||
| <200 | 35.0 | — | |
| 200–349 | 26.7 | — | |
| 350–499 | 20.5 | — | |
| ≥500 | 17.9 | — |
HIV-infected and HIV-uninfected subjects were matched on age (5-year groups), gender, medical center, and initial calendar year of follow-up. P values were obtained from χ2 tests for categorical variables and t tests for continuous variables. Some data were missing on race/ethnicity (3.3% of HIV-infected and 21.0% of HIV-uninfected subjects), HIV-transmission risk group (20.5%), and CD4 count at ART initiation (0.2%).