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. Author manuscript; available in PMC: 2018 Apr 10.
Published in final edited form as: Cancer Cell. 2017 Mar 23;31(4):591–606.e6. doi: 10.1016/j.ccell.2017.02.013

Figure 8. FOXM1 Reinstates the Tumor Growth of GSCs with Depleted ALKBH5 or FOXM1-AS.

Figure 8

(A) qPCR analysis of the indicated mRNAs in GSC11 cells with or without ALKBH5 knockdown and in GSC11 cells with ALKBH5 knockdown rescued by exogenous FOXM1. Error bars: ± SEM of 3 independent experiments. *p<0.05, **p<0.01 (shALKBH5 + FOXM1 versus + Vector)

(B) Top, representative images of H&E staining for tumor formation. Bottom, histograms show tumor volumes. Error bars: ± SEM. n=8.

(C) Representative IF images of the indicated proteins in GSC17 xenografts. Scale bar, 50 μm.

See also Figure S8