Table 2.
Osteoporosis-associated differential urinary proteins analyzed by a quantitative MS/MS.
| Accession # | Protein Name | Normalized Spectrum Count |
Plasma Level in
Osteoporosis |
References | ||
|---|---|---|---|---|---|---|
| Young | Sham | OVX | ||||
| P17475 | A1AT | 0 | 0 | 16 | Down | [22] |
| Q63213 | Alpha-2u globulin | 17 | 10 | 43 | NRa | |
| Q7TPI9 | Antithrombin-III | 0 | 0 | 8 | NR | |
| P04639 | Apolipoprotein A-I | 7 | 10 | 27 | NR | |
| M0R8A9 | Apolipoprotein A-IV | 0 | 0 | 27 | NR | |
| P26644 | Beta-2-glycoprotein 1 | 8 | 10 | 26 | NR | |
| Q8K3U6 | Coagulation factor VII | 0 | 0 | 32 | NR | |
| P01026 | Complement C3 | 0 | 0 | 11 | NR | |
| Q8VHC1 | Cystatin-M | 0 | 0 | 10 | NR | |
| P14740 | Dipeptidyl peptidase 4 | 27 | 24 | 58 | Up | [23] |
| Q62894 | Extracellular matrix protein 1 | 0 | 0 | 12 | Down | [24] |
| Q7TQ70 | Fibrinogen alpha chain | 0 | 0 | 14 | Up | [25] |
| P07314 | Gamma-glutamyltranspeptidase | 17 | 12 | 44 | Up | [26] |
| P20059 | Hemopexin | 0 | 0 | 9 | NR | |
| P35572 | Insulin-like growth factor-binding protein | 0 | 0 | 8 | Down | [27] |
| P28826 | Meprin A beta-subunit | 7 | 10 | 52 | NR | |
| P12346 | Serotransferrin | 7 | 9 | 50 | Up | [28] |
| P07724 | Serum albumin | 214 | 287 | 718 | No association | [29] |
| P02767 | Transthyretin | 0 | 0 | 8 | Up | [30] |
| P23593 | Apolipoprotein D | 16 | 25 | 8 | NR | |
| O08779 | CD44 antigen | 29 | 11 | 0 | NR | |
| Q9Z0M0 | Complement decay-accelerating factor | 11 | 17 | 0 | NR | |
| Q08420 | Extracellular superoxide dismutase [Cu-Zn] | 11 | 15 | 0 | Down | [31] |
| Q6AXM6 | Intercellular adhesion molecule 2 | 12 | 9 | 0 | NR | |
| Q63691 | Monocyte differentiation antigen CD14 | 8 | 11 | 0 | NR | |
| P08721 | Osteopontin | 12 | 10 | 0 | Down | [32] |
| Q56A20 | Phosphoinositide-3-kinase-interacting protein | 21 | 23 | 0 | NR | |
| P07632 | Superoxide dismutase [Cu-Zn] | 19 | 19 | 9 | Down | [17] |
| P34901 | Syndecan-4 | 29 | 22 | 0 | NR | |
| D3ZAE6 | Vasorin | 44 | 41 | 13 | NR | |
a NR, not reported