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MRI - nodule-in-nodule sign – an early stage of HCC. The lesion (arrow) is hyperintense in T2-weighted images in coronal plane without fat saturation (a) and in axial plane with fat saturation (b). The early HCC shows intense enhancement in hepatic arterial phase (c) with washout in equilibrium phase (d) and diffusion restriction in diffusion weighted imaging (b=800s/mm2, e).
