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. 2017 Mar 7;7:105. doi: 10.1038/s41598-017-00179-8

Table 1.

Results of the spatial scan analysis of female breast cancer mortality at the county level in Shandong for the years 2011 to 2013.

Cluster County amount Cases Expected RR LLR P value
Total without adjustment for age
Most likely cluster 25 2265 1651 1.46 125.69 <0.001
Secondary cluster 1 1 399 196 2.01 78.17 <0.001
Secondary cluster 2 1 174 79 2.24 46.31 <0.001
Secondary cluster 3 3 443 287 1.54 36.65 <0.001
Secondary cluster 4 9 942 751 1.31 30.47 <0.001
Secondary cluster 5 1 197 124 1.56 17.15 <0.001
Secondary cluster 6 1 90 55 1.59 8.29 <0.01
Total adjusted for age
Most likely cluster 7 668 420 1.64 65.94 <0.001
Secondary cluster 1 1 133 54 2.48 40.97 <0.001
Secondary cluster 2 24 1315 1088 1.25 25.95 <0.001
Secondary cluster 3 1 154 85 1.82 22.47 <0.001
Secondary cluster 4 9 633 516 1.25 13.19 <0.001
Secondary cluster 5 1 66 38 1.77 8.86 <0.05
Urban without adjustment for age
Most likely cluster 3 211 94 2.32 55.61 <0.001
Secondary cluster 1 5 287 171 1.73 34.21 <0.001
Secondary cluster 2 19 871 706 1.29 21.74 <0.001
Secondary cluster 3 7 489 396 1.27 11.31 <0.01
Urban adjusted for age
Most likely cluster 5 233 119 2.04 44.77 <0.001
Secondary cluster 1 3 153 65 2.42 43.99 <0.001
Secondary cluster 2 1 86 50 1.73 10.69 <0.01
Rural without adjustment for age
Most likely cluster 59 3789 3159 1.42 110.66 <0.001
Secondary cluster 1 8 692 467 1.53 51.16 <0.001
Secondary cluster 2 1 124 61 2.05 25.28 <0.001
Secondary cluster 3 1 162 100 1.63 16.2 <0.001
Rural adjusted for age
Most likely cluster 8 504 318 1.65 49.7 <0.001
Secondary cluster 1 59 2453 2155 1.28 36.24 <0.001
Secondary cluster 2 1 93 42 2.26 23.69 <0.001
Secondary cluster 3 1 127 68 1.88 20.28 <0.001

Note: “Most likely cluster” was defined when the maximum log likelihood ratio (LLR) with statistical significance was detected by Monte Carlo simulation in the spatial analysis; the other LLR values with statistical significance were identified as the “Secondary cluster”. The relative risk (RR) was the ratio of the mortality inside a cluster area to the mortality outside a cluster area.