Table 3.
Summary results for statistically nominal and significant associations between SNPs and lipids.
| Gene | SNP | Birth (N = 456) | 3y (N = 421) | 5y (N = 361) | Mixed Model Age Adjusted | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Beta | SE | p-value | Beta | SE | p-value | Beta | SE | p-value | Beta | SE | p-value | ||
| LDL | |||||||||||||
| ANGPTL3 | rs2131925 | 0.020 | 0.025 | 4.30 × 10−1 | 0.043 | 0.021 | 4.31 × 10 −2 | 0.041 | 0.023 | 8.36 × 10−2 | 0.029 | 0.018 | 1.01 × 10−1 |
| LDLRAP1 | rs12027135 | −0.017 | 0.022 | 4.45 × 10−1 | 0.011 | 0.019 | 5.45 × 10−1 | 0.046 | 0.021 | 2.74 × 10 −2 | 0.009 | 0.016 | 5.70 × 10−1 |
| ABCG5 | rs6756629 | −0.017 | 0.049 | 7.34 × 10−1 | 0.102 | 0.041 | 1.32 × 10 −2 | 0.113 | 0.044 | 1.01 × 10 −2 | 0.073 | 0.034 | 2.94 × 10−2 |
| CMTM6 | rs7640978 | 0.030 | 0.043 | 4.89 × 10−1 | 0.022 | 0.037 | 5.61 × 10−1 | 0.083 | 0.040 | 3.98 × 10 −2 | 0.050 | 0.030 | 9.72 × 10−2 |
| DOK7 | rs6831256 | 0.037 | 0.024 | 1.15 × 10−1 | 0.061 | 0.019 | 1.62 × 10 −3 | 0.035 | 0.021 | 1.04 × 10−1 | 0.030 | 0.016 | 6.96 × 10−2 |
| HMGCR | rs12916 | 0.022 | 0.024 | 3.59 × 10−1 | −0.045 | 0.019 | 1.80 × 10 −2 | 0.018 | 0.021 | 3.92 × 10−1 | 0.009 | 0.016 | 5.90 × 10−1 |
| TIMD4 | rs6882076 | 0.002 | 0.024 | 9.26 × 10−1 | 0.049 | 0.020 | 1.22 × 10 −2 | 0.057 | 0.021 | 8.29 × 10−3 | 0.028 | 0.016 | 8.66 × 10−2 |
| FRK | rs3798236 | −0.040 | 0.025 | 1.14 × 10−1 | −0.065 | 0.020 | 1.30 × 10 −3 | 0.013 | 0.022 | 5.52 × 10−1 | −0.013 | 0.018 | 4.60 × 10−1 |
| MYLIP/GMPR | rs2327951 | 0.000 | 0.027 | 9.93 × 10−1 | 0.061 | 0.022 | 6.47 × 10 −3 | 0.051 | 0.025 | 3.79 × 10−2 | 0.026 | 0.019 | 1.66 × 10−1 |
| ABO | rs635634 | −0.018 | 0.030 | 5.39 × 10−1 | 0.053 | 0.025 | 3.52 × 10 −2 | 0.062 | 0.026 | 1.97 × 10−2 | 0.017 | 0.020 | 4.16 × 10−1 |
| BUD13 | rs12292921 | −0.048 | 0.051 | 3.44 × 10−1 | −0.095 | 0.043 | 2.72 × 10 −2 | −0.077 | 0.048 | 1.09 × 10−1 | −0.078 | 0.035 | 2.75 × 10 −2 |
| HNF1A | rs1169288 | 0.011 | 0.026 | 6.74 × 10−1 | −0.041 | 0.020 | 3.88 × 10 −2 | −0.008 | 0.021 | 7.12 × 10−1 | 0.005 | 0.018 | 7.79 × 10−1 |
| NYNRIN | rs8017377 | −0.029 | 0.023 | 2.12 × 10−1 | 0.048 | 0.019 | 1.22 × 10 −2 | 0.042 | 0.020 | 3.89 × 10−2 | 0.006 | 0.016 | 7.08 × 10−1 |
| DLG4 | rs314253 | 0.003 | 0.026 | 8.91 × 10−1 | 0.054 | 0.021 | 1.05 × 10 −2 | 0.032 | 0.023 | 1.73 × 10−1 | 0.030 | 0.018 | 9.21 × 10−2 |
| C17orf157 | rs12452315 | 0.055 | 0.023 | 1.85 × 10−2 | 0.010 | 0.020 | 6.14 × 10−1 | 0.027 | 0.022 | 2.18 × 10−1 | 0.034 | 0.016 | 3.59 × 10 −2 |
| CILP2 | rs10401969 | 0.030 | 0.048 | 5.26 × 10−1 | 0.088 | 0.038 | 2.11 × 10 −2 | 0.045 | 0.045 | 3.18 × 10−1 | 0.049 | 0.033 | 1.36 × 10−1 |
| LDLR | rs6511720 | 0.052 | 0.035 | 1.42 × 10−1 | 0.044 | 0.029 | 1.31 × 10−1 | 0.063 | 0.032 | 5.50 × 10−2 | 0.057 | 0.024 | 1.80 × 10 −2 |
| TOMM40/APOE/APOC1 | rs157580 | 0.076 | 0.024 | 1.54 × 10 −3 | 0.031 | 0.020 | 1.31 × 10−1 | 0.008 | 0.022 | 7.10 × 10−1 | 0.039 | 0.017 | 1.86 × 10 −2 |
| MAFB | rs2902940 | 0.023 | 0.025 | 3.76 × 10−1 | 0.066 | 0.020 | 7.63 × 10 −4 | 0.025 | 0.021 | 2.45 × 10−1 | 0.021 | 0.017 | 2.33 × 10−1 |
| SPTLC3 | rs364585 | −0.001 | 0.025 | 9.73 × 10−1 | 0.045 | 0.021 | 2.87 × 10 −2 | 0.024 | 0.023 | 2.87 × 10−1 | 0.023 | 0.017 | 1.73 × 10−1 |
| GS | GS | 0.007 | 0.004 | 7.09 × 10−2 | 0.019 | 0.003 | 2.40 × 10 −9 | 0.020 | 0.003 | 2.56 × 10−9 | 0.013 | 0.003 | 2.82 × 10 −7 |
| TOTAL CHOLESTEROL | |||||||||||||
| EVI5 | rs6603981 | −0.043 | 0.019 | 2.74 × 10 −2 | 0.008 | 0.015 | 6.02 × 10−1 | 0.013 | 0.016 | 4.06 × 10−1 | −0.021 | 0.013 | 1.18 × 10−1 |
| PCSK9 | rs2479409 | 0.023 | 0.016 | 1.56 × 10−1 | 0.027 | 0.013 | 3.55 × 10 −2 | 0.005 | 0.013 | 6.78 × 10−1 | 0.013 | 0.011 | 2.19 × 10−1 |
| ABCG5 | rs6756629 | 0.010 | 0.032 | 7.41 × 10−1 | 0.059 | 0.026 | 2.57 × 10 −2 | 0.059 | 0.026 | 2.32 × 10 −2 | 0.048 | 0.022 | 2.74 × 10 −2 |
| ABCG8 | rs6544713 | 0.011 | 0.018 | 5.31 × 10−1 | −0.034 | 0.014 | 1.15 × 10 −2 | −0.001 | 0.013 | 9.49 × 10−1 | 0.005 | 0.012 | 6.99 × 10−1 |
| GCKR | rs1260326 | −0.010 | 0.016 | 5.22 × 10−1 | −0.028 | 0.012 | 2.23 × 10 −2 | 0.005 | 0.013 | 7.13 × 10−1 | −0.001 | 0.011 | 9.55 × 10−1 |
| RAB3GAP1 | rs7570971 | 0.003 | 0.016 | 8.41 × 10−1 | 0.037 | 0.013 | 4.73 × 10 −3 | 0.023 | 0.013 | 6.64 × 10−2 | 0.010 | 0.011 | 3.59 × 10−1 |
| DOK7 | rs6831256 | 0.000 | 0.015 | 9.82 × 10−1 | 0.042 | 0.012 | 6.42 × 10 −4 | 0.033 | 0.012 | 8.36 × 10 −3 | 0.011 | 0.011 | 2.82 × 10−1 |
| HMGCR | rs12916 | 0.024 | 0.016 | 1.30 × 10−1 | −0.036 | 0.012 | 2.73 × 10 −3 | −0.004 | 0.012 | 7.21 × 10−1 | 0.004 | 0.011 | 6.81 × 10−1 |
| TIMD4 | rs6882076 | −0.012 | 0.015 | 4.53 × 10−1 | 0.031 | 0.012 | 1.34 × 10 −2 | 0.028 | 0.013 | 2.89 × 10−2 | 0.009 | 0.010 | 3.72 × 10−1 |
| FRK | rs3798236 | −0.016 | 0.017 | 3.44 × 10−1 | −0.038 | 0.013 | 3.59 × 10 −3 | 0.002 | 0.013 | 8.66 × 10−1 | −0.001 | 0.011 | 9.25 × 10−1 |
| HLA | rs3177928 | 0.003 | 0.022 | 8.75 × 10−1 | 0.051 | 0.018 | 4.27 × 10 −3 | 0.006 | 0.018 | 7.51 × 10−1 | 0.013 | 0.015 | 3.93 × 10−1 |
| LPA | rs1564348 | −0.049 | 0.021 | 1.72 × 10 −2 | 0.023 | 0.017 | 1.78 × 10−1 | 0.014 | 0.017 | 4.15 × 10−1 | −0.018 | 0.014 | 2.04 × 10−1 |
| MIR148A | rs4722551 | −0.076 | 0.021 | 2.50 × 10 −4 | 0.031 | 0.017 | 6.92 × 10−2 | 0.024 | 0.017 | 1.72 × 10−1 | −0.024 | 0.014 | 9.35 × 10−2 |
| NAT2 | rs4921914 | −0.037 | 0.018 | 4.37 × 10 −2 | −0.030 | 0.015 | 3.94 × 10−2 | −0.021 | 0.015 | 1.54 × 10−1 | −0.023 | 0.012 | 6.94 × 10−2 |
| ABCA1 | rs1883025 | 0.034 | 0.017 | 4.45 × 10 −2 | 0.016 | 0.014 | 2.31 × 10−1 | 0.002 | 0.014 | 8.68 × 10−1 | 0.015 | 0.012 | 2.07 × 10−1 |
| ABO | rs635634 | −0.003 | 0.019 | 8.60 × 10−1 | 0.036 | 0.016 | 2.54 × 10 −2 | 0.043 | 0.015 | 5.85 × 10 −3 | 0.014 | 0.013 | 2.98 × 10−1 |
| TTC39B | rs581080 | −0.002 | 0.019 | 9.06 × 10−1 | 0.039 | 0.016 | 1.20 × 10 −2 | 0.024 | 0.016 | 1.24 × 10−1 | 0.007 | 0.013 | 5.75 × 10−1 |
| BUD13 | rs12292921 | −0.050 | 0.033 | 1.30 × 10−1 | −0.046 | 0.027 | 9.08 × 10−2 | −0.054 | 0.028 | 5.79 × 10−2 | −0.052 | 0.023 | 2.29 × 10 −2 |
| HNF1A | rs1169288 | −0.015 | 0.017 | 3.84 × 10−1 | −0.026 | 0.013 | 4.36 × 10 −2 | −0.017 | 0.013 | 1.79 × 10−1 | −0.005 | 0.011 | 6.70 × 10−1 |
| DLG4 | rs314253 | −0.016 | 0.017 | 3.38 × 10−1 | 0.036 | 0.013 | 8.47 × 10 −3 | 0.021 | 0.014 | 1.28 × 10−1 | 0.012 | 0.011 | 2.73 × 10−1 |
| C17orf157 | rs12452315 | 0.045 | 0.015 | 2.99 × 10 −3 | 0.007 | 0.013 | 6.05 × 10−1 | 0.015 | 0.013 | 2.48 × 10−1 | 0.026 | 0.010 | 1.41 × 10 −2 |
| LIPG | rs7240405 | 0.000 | 0.021 | 9.95 × 10−1 | 0.044 | 0.018 | 1.44 × 10 −2 | 0.020 | 0.018 | 2.60 × 10−1 | 0.008 | 0.015 | 5.98 × 10−1 |
| FUT2 | rs492602 | 0.005 | 0.016 | 7.62 × 10−1 | 0.025 | 0.013 | 5.51 × 10−2 | 0.028 | 0.013 | 2.73 × 10 −2 | 0.014 | 0.011 | 1.82 × 10−1 |
| LDLR | rs6511720 | 0.026 | 0.023 | 2.66 × 10−1 | 0.033 | 0.019 | 7.54 × 10−2 | 0.028 | 0.019 | 1.40 × 10−1 | 0.035 | 0.016 | 2.60 × 10 −2 |
| TOMM40/APOE/APOC1 | rs2075650 | 0.019 | 0.021 | 3.52 × 10−1 | 0.073 | 0.017 | 2.13 × 10 −5 | 0.058 | 0.016 | 5.50 × 10 −4 | 0.042 | 0.014 | 3.29 × 10 −3 |
| FER1LA | rs2277862 | 0.043 | 0.022 | 5.18 × 10−2 | 0.049 | 0.018 | 5.72 × 10 −3 | 0.047 | 0.017 | 7.30 × 10 −3 | 0.031 | 0.015 | 4.28 × 10 −2 |
| TOP1 | rs6065311 | −0.007 | 0.016 | 6.42 × 10−1 | −0.007 | 0.013 | 5.90 × 10−1 | −0.026 | 0.013 | 4.59 × 10 −2 | −0.012 | 0.011 | 2.87 × 10−1 |
| GS | GS | −0.001 | 0.002 | 7.31 × 10−1 | 0.009 | 0.002 | 7.27 × 10 −7 | 0.009 | 0.002 | 4.07 × 10 −6 | 0.004 | 0.002 | 3.78 × 10 −3 |
| HDL | |||||||||||||
| ZNF648 | rs1689800 | 0.013 | 0.022 | 5.63 × 10−1 | −0.045 | 0.016 | 6.27 × 10 −3 | −0.001 | 0.019 | 9.70 × 10−1 | 0.001 | 0.014 | 9.54 × 10−1 |
| APOB | rs1042034 | 0.028 | 0.026 | 2.85 × 10−1 | 0.042 | 0.021 | 4.04 × 10 −2 | 0.039 | 0.023 | 9.01 × 10−2 | 0.026 | 0.017 | 1.22 × 10−1 |
| ATG7 | rs2606736 | −0.045 | 0.022 | 4.30 × 10 −2 | 0.000 | 0.017 | 9.98 × 10−1 | 0.006 | 0.019 | 7.61 × 10−1 | −0.031 | 0.014 | 2.45 × 10 −2 |
| FAM13A | rs3822072 | −0.018 | 0.021 | 3.88 × 10−1 | 0.033 | 0.015 | 2.73 × 10 −2 | 0.011 | 0.017 | 5.28 × 10−1 | −0.006 | 0.013 | 6.61 × 10−1 |
| ARL15 | rs6450176 | 0.025 | 0.024 | 2.86 × 10−1 | −0.044 | 0.018 | 1.32 × 10 −2 | −0.027 | 0.020 | 1.78 × 10−1 | −0.002 | 0.015 | 8.92 × 10−1 |
| RSPO3 | rs1936800 | 0.032 | 0.022 | 1.43 × 10−1 | −0.033 | 0.015 | 3.25 × 10 −2 | -0.017 | 0.017 | 3.20 × 10−1 | 0.015 | 0.013 | 2.48 × 10−1 |
| VEGFA | rs998584 | 0.025 | 0.021 | 2.26 × 10−1 | −0.012 | 0.016 | 4.46 × 10−1 | 0.025 | 0.018 | 1.70 × 10−1 | 0.027 | 0.013 | 3.95 × 10 −2 |
| DAGLB | rs702485 | 0.010 | 0.022 | 6.51 × 10−1 | 0.020 | 0.017 | 2.43 × 10−1 | 0.042 | 0.019 | 3.19 × 10 −2 | 0.025 | 0.014 | 7.54 × 10−2 |
| IKZF1 | rs4917014 | 0.031 | 0.023 | 1.76 × 10−1 | −0.039 | 0.017 | 2.14 × 10 −2 | −0.035 | 0.019 | 6.56 × 10−2 | 0.016 | 0.014 | 2.56 × 10−1 |
| KLF14 | rs4731702 | 0.009 | 0.021 | 6.62 × 10−1 | 0.031 | 0.016 | 4.68 × 10 −2 | 0.010 | 0.017 | 5.83 × 10−1 | 0.003 | 0.013 | 8.44 × 10−1 |
| TRIB1 | rs2954029 | 0.035 | 0.023 | 1.25 × 10−1 | 0.036 | 0.017 | 3.32 × 10 −2 | 0.022 | 0.019 | 2.45 × 10−1 | 0.013 | 0.014 | 3.48 × 10−1 |
| TRPS1 | rs2293889 | 0.019 | 0.021 | 3.70 × 10−1 | 0.038 | 0.015 | 1.29 × 10 −2 | 0.017 | 0.017 | 3.13 × 10−1 | 0.009 | 0.013 | 5.01 × 10−1 |
| ABCA1 | rs1883025 | 0.048 | 0.024 | 4.52 × 10 −2 | 0.052 | 0.018 | 3.20 × 10 −3 | 0.046 | 0.020 | 2.02 × 10 −2 | 0.038 | 0.015 | 8.27 × 10 −3 |
| TTC39B | rs581080 | −0.001 | 0.027 | 9.63 × 10−1 | 0.045 | 0.020 | 2.51 × 10 −2 | 0.015 | 0.023 | 4.97 × 10−1 | 0.008 | 0.017 | 6.18 × 10−1 |
| AMPD3 | rs2923084 | −0.035 | 0.027 | 1.98 × 10−1 | 0.043 | 0.020 | 3.78 × 10 −2 | 0.114 | 0.024 | 1.89 × 10 −6 | 0.015 | 0.017 | 3.69 × 10−1 |
| FADS1-2-3 | rs174546 | −0.012 | 0.022 | 5.99 × 10−1 | 0.049 | 0.017 | 3.44 × 10 −3 | 0.026 | 0.019 | 1.69 × 10−1 | 0.017 | 0.014 | 2.04 × 10−1 |
| LRP4 | rs3136441 | 0.003 | 0.031 | 9.12 × 10−1 | −0.048 | 0.023 | 3.71 × 10 −2 | −0.044 | 0.027 | 9.86 × 10−2 | −0.001 | 0.020 | 9.40 × 10−1 |
| MADD/FOLH1 | rs7395662 | 0.010 | 0.022 | 6.52 × 10−1 | 0.051 | 0.016 | 1.87 × 10 −3 | 0.041 | 0.019 | 3.01 × 10 −2 | 0.021 | 0.014 | 1.29 × 10−1 |
| MOGAT2 | rs499974 | −0.042 | 0.029 | 1.49 × 10−1 | −0.042 | 0.023 | 6.13 × 10−2 | −0.052 | 0.026 | 4.87 × 10 −2 | −0.032 | 0.018 | 8.12 × 10−2 |
| PCNXL3 | rs12801636 | −0.028 | 0.026 | 2.84 × 10−1 | −0.036 | 0.019 | 6.93 × 10−2 | −0.053 | 0.022 | 1.73 × 10 −2 | −0.027 | 0.016 | 1.02 × 10−1 |
| LRP1 | rs11613352 | −0.069 | 0.025 | 5.91 × 10 −3 | 0.002 | 0.019 | 9.06 × 10−1 | 0.009 | 0.021 | 6.54 × 10−1 | −0.029 | 0.015 | 6.01 × 10−2 |
| MMAB/MVK | rs7298565 | 0.065 | 0.020 | 1.48 × 10 −3 | −0.015 | 0.015 | 3.13 × 10−1 | −0.011 | 0.017 | 5.04 × 10−1 | 0.026 | 0.013 | 4.10 × 10 −2 |
| SCARB1 | rs838880 | 0.018 | 0.023 | 4.50 × 10−1 | 0.008 | 0.018 | 6.32 × 10−1 | 0.020 | 0.020 | 2.99 × 10−1 | 0.024 | 0.014 | 8.93 × 10 −2 |
| LIPC | rs1077834 | 0.058 | 0.025 | 2.34 × 10 −2 | 0.072 | 0.019 | 2.32 × 10 −4 | 0.029 | 0.023 | 2.07 × 10−1 | 0.045 | 0.016 | 4.99 × 10 −3 |
| CETP | rs3764261 | 0.047 | 0.023 | 4.12 × 10 −2 | 0.055 | 0.017 | 1.65 × 10 −3 | 0.068 | 0.020 | 7.62 × 10 −4 | 0.064 | 0.014 | 7.11 × 10 −6 |
| CMIP | rs2925979 | 0.019 | 0.024 | 4.33 × 10−1 | −0.062 | 0.018 | 5.31 × 10 −4 | −0.032 | 0.020 | 1.14 × 10−1 | −0.012 | 0.015 | 4.36 × 10−1 |
| LCAT | rs16942887 | 0.015 | 0.031 | 6.32 × 10−1 | 0.048 | 0.024 | 4.55 × 10 −2 | 0.020 | 0.028 | 4.81 × 10−1 | 0.017 | 0.020 | 3.84 × 10−1 |
| ABCA8 | rs4148008 | −0.035 | 0.022 | 1.12 × 10−1 | −0.047 | 0.017 | 5.73 × 10 −3 | −0.035 | 0.019 | 6.83 × 10−2 | −0.039 | 0.014 | 4.64 × 10 −3 |
| PGS1 | rs4129767 | 0.064 | 0.022 | 3.54 × 10 −3 | −0.036 | 0.016 | 2.61 × 10 −2 | −0.027 | 0.018 | 1.32 × 10−1 | 0.021 | 0.013 | 1.26 × 10−1 |
| PLTP | rs6065906 | 0.001 | 0.027 | 9.67 × 10−1 | 0.054 | 0.021 | 8.98 × 10 −3 | 0.053 | 0.023 | 2.39 × 10 −2 | 0.017 | 0.017 | 3.09 × 10−1 |
| GS | GS | 0.006 | 0.003 | 2.15 × 10 −2 | 0.003 | 0.002 | 1.59 × 10−1 | 0.004 | 0.002 | 1.26 × 10−1 | 0.005 | 0.002 | 3.27 × 10 −3 |
| TRIGLYCERIDES | |||||||||||||
| APOB | rs1042034 | −0.025 | 0.044 | 5.73 × 10−1 | 0.069 | 0.033 | 3.72 × 10 −2 | 0.000 | 0.038 | 9.95 × 10−1 | 0.011 | 0.026 | 6.79 × 10−1 |
| GCKR | rs1260326 | 0.056 | 0.036 | 1.28 × 10−1 | 0.098 | 0.025 | 8.72 × 10 −5 | 0.025 | 0.030 | 3.98 × 10−1 | 0.047 | 0.021 | 2.61 × 10 −2 |
| IRS1 | rs2972146 | −0.086 | 0.039 | 2.92 × 10 −2 | −0.010 | 0.029 | 7.41 × 10−1 | −0.020 | 0.034 | 5.56 × 10−1 | −0.037 | 0.023 | 1.10 × 10−1 |
| MSL2L1 | rs645040 | −0.003 | 0.041 | 9.48 × 10−1 | 0.079 | 0.030 | 9.26 × 10 −3 | −0.021 | 0.036 | 5.70 × 10−1 | 0.010 | 0.024 | 6.90 × 10−1 |
| MAP3K1 | rs9686661 | 0.004 | 0.043 | 9.26 × 10−1 | 0.090 | 0.031 | 3.31 × 10 −3 | 0.045 | 0.037 | 2.23 × 10−1 | 0.029 | 0.025 | 2.40 × 10−1 |
| MLXIPL | rs17145738 | −0.011 | 0.056 | 8.49 × 10−1 | 0.082 | 0.039 | 3.79 × 10 −2 | −0.084 | 0.046 | 6.83 × 10−2 | −0.029 | 0.033 | 3.72 × 10−1 |
| TRIB1 | rs2954029 | 0.037 | 0.038 | 3.30 × 10−1 | 0.074 | 0.027 | 5.94 × 10 −3 | −0.025 | 0.031 | 4.23 × 10−1 | 0.015 | 0.022 | 4.92 × 10−1 |
| BUD13 | rs12292921 | 0.129 | 0.076 | 9.07 × 10−2 | −0.057 | 0.056 | 3.17 × 10−1 | −0.145 | 0.067 | 3.16 × 10 −2 | −0.019 | 0.045 | 6.80 × × 10−1 |
| FADS1-2-3 | rs174546 | −0.032 | 0.036 | 3.77 × 10−1 | 0.077 | 0.027 | 4.02 × 10 −3 | 0.054 | 0.032 | 8.98 × 10−2 | 0.016 | 0.021 | 4.50 × 10−1 |
| LRP1 | rs11613352 | −0.043 | 0.041 | 2.99 × 10−1 | 0.009 | 0.030 | 7.58 × 10−1 | 0.079 | 0.035 | 2.39 × 10 −2 | 0.005 | 0.024 | 8.36 × 10−1 |
| ZNF664 | rs11057408 | −0.066 | 0.038 | 8.33 × 10−2 | −0.062 | 0.027 | 2.34 × 10 −2 | −0.020 | 0.032 | 5.24 × 10−1 | −0.033 | 0.022 | 1.32 × 10−1 |
| APOC2/APOCL/APOE | rs439401 | −0.043 | 0.036 | 2.34 × 10−1 | −0.017 | 0.025 | 4.96 × 10−1 | 0.076 | 0.029 | 8.92 × 10 −3 | 0.016 | 0.021 | 4.37 × 10−1 |
| CILP2 | rs10401969 | −0.090 | 0.072 | 2.09 × 10−1 | 0.146 | 0.050 | 3.40 × 10−3 | 0.199 | 0.063 | 1.64 × 10 −3 | 0.047 | 0.041 | 2.52 × 10−1 |
| INSR | rs7248104 | 0.028 | 0.036 | 4.44 × 10−1 | 0.017 | 0.025 | 4.98 × 10−1 | 0.072 | 0.029 | 1.39 × 10 −2 | 0.057 | 0.021 | 6.65 × 10 −3 |
| PLTP | rs6065906 | 0.016 | 0.045 | 7.16 × 10−1 | 0.069 | 0.033 | 3.91 × 10 −2 | 0.053 | 0.039 | 1.72 × 10−1 | 0.022 | 0.027 | 4.11 × 10−1 |
| GS | GS | 0.000 | 0.007 | 9.86 × 10−1 | 0.010 | 0.005 | 4.37 × 10 −2 | 0.014 | 0.006 | 1.06 × 10 −2 | 0.008 | 0.004 | 3.08 × 10 −2 |
Beta and SE at birth, 3 year and 5 year are natural logarithm of the lipid level trait in mg/dl. The unit of beta and SE after linear mixed model is natural logarithm of the lipid level trait in mg/dl per year.