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. 2017 Mar 2;7:113. doi: 10.1038/s41598-017-00155-2

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© The Author(s) 2017

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hERG inhibiting (S4-S5_L (+3)) and activating peptides (S6_T (−3)) are aligned with KCNQ1 inhibiting and activating peptides. Same as in Fig. 1B, onto which the results obtained with hERG have been added. A check sign (✓) indicates that the S4-S5_L peptide inhibits the channel and that the S6_T peptide activates the channel.